Sökning: "autoimmune disorders"

Visar resultat 1 - 5 av 125 avhandlingar innehållade orden autoimmune disorders.

1. 1. Associated disorders in celiac disease

   Författare :Peter Elfström; Jonas F. Ludvigsson; Anders Ekbom; Peter Green; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addison; autoimmune; biopsy; celiac; child; cohort study; cancer; heart; liver; lymphoma; thyroid; Paediatric medicine; Pediatrisk medicin; MEDICINE; MEDICIN; Pediatrik; Pediatrics; Epidemiology; Epidemiologi; Medicin; Medicine;

   Sammanfattning : Background: Celiac disease (CD) is an autoimmune disorder that affects genetically susceptible individuals and is induced by dietary gluten. Treatment consists of a lifelong gluten-free diet. CD is common and affects about 1% of the general population. LÄS MER

3. 2. Transglutaminase and peptidylarginine deiminase in the pathogenesis of autoimmune diseases

   Författare :Bodil Roth; Gastroenterologi; []
   Nyckelord :multiple sclerosis; pathogenesis; peptidylargininedeiminase; transglutaminase.; Sjögren’s syndrome; autoimmune; Alzheimer’s disease;

   Sammanfattning : Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific glutamine residues of gliadins have been identified. LÄS MER

4. 3. Markers of Infection in Childhood Autoimmune Diabetes and Related Disorders

   Författare :Anna-Lena Nilsson; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmune type 1 diabetes Ljungan virus antibodies Islet autoantibodies HLA;

   Sammanfattning : The main aim of this thesis was to contribute to the knowledge about mechanisms involved in the development of type 1 diabetes (T1D) and other autoimmune diseases in children. Immune markers in relation to genetic propensity in children with autoimmune disease, mainly T1D and a small group of juvenile idiopathic arthritis (JIA) and thyroiditis (THYR), as well as healthy controls have been studied. LÄS MER

5. 4. Ultraviolet light, autoimmune disorders and the etiology of malignant lymphomas

   Författare :Karin Ekström Smedby; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Non-Hodgkin lymphoma; Hodgkin lymphoma; ultraviolet light; autoimmune disorders; rheumatoid arthritis; celiac disease; risk factors; cohort; case-control; epidemiology;

   Sammanfattning : Malignant lymphomas constitute a clinically and morphologically diverse group of malignancies that may also differ etiologically. The incidence of the most common non-Hodgkin lymphomas (NHL) has increased dramatically worldwide during the past decades. LÄS MER

7. 5. Genetic Studies of Rheumatoid Arthritis using Animal Models

   Författare :Niklas Nordquist; William Dietrich; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. LÄS MER