Sökning: "autoimmune disorders"
Visar resultat 1 - 5 av 111 avhandlingar innehållade orden autoimmune disorders.
Sammanfattning : Background: Celiac disease (CD) is an autoimmune disorder that affects genetically susceptible individuals and is induced by dietary gluten. Treatment consists of a lifelong gluten-free diet. CD is common and affects about 1% of the general population. LÄS MER
Sammanfattning : Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific glutamine residues of gliadins have been identified. LÄS MER
Sammanfattning : The main aim of this thesis was to contribute to the knowledge about mechanisms involved in the development of type 1 diabetes (T1D) and other autoimmune diseases in children. Immune markers in relation to genetic propensity in children with autoimmune disease, mainly T1D and a small group of juvenile idiopathic arthritis (JIA) and thyroiditis (THYR), as well as healthy controls have been studied. LÄS MER
Sammanfattning : Malignant lymphomas constitute a clinically and morphologically diverse group of malignancies that may also differ etiologically. The incidence of the most common non-Hodgkin lymphomas (NHL) has increased dramatically worldwide during the past decades. LÄS MER
Sammanfattning : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. LÄS MER