Sökning: "autoantigen"

Visar resultat 6 - 10 av 66 avhandlingar innehållade ordet autoantigen.

  1. 6. Experimental studies on autoantigen regulation in insulin-dependent diabetes mellitus

    Författare :Elisabeth Björk; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 7. Glutamate decarboxylase as an autoantigen in type 1 diabetes mellitus

    Författare :Lício A. Velloso; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 8. Molecular characterization of the Ro52 autoantigen and its disease related epitopes

    Författare :Lars Ottosson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ro52; Sjögren s syndrome; autoantibodies; congenital heart block; molecular characterization; TRIM; RBCC; Zn2 ;

    Sammanfattning : The presence of high titers of autoantibodies in patient sera is characteristic for the autoimmune disorder Sjögren s syndrome. The major targets for these autoantibodies are three intracellular proteins Ro52, Ro60 and La. It is still unclear why these proteins become targets for the immune system, and how this autoreactivity is triggered. LÄS MER

  5. 9. Tumour Biological Factors Characterizing Metastasizing Serotonin-producing Ileocaecal Carcinoids

    Författare :Janet Lynn Cunningham; Eva Tiensuu Janson; Kjell Öberg; Irvin M. Modlin; Uppsala universitet; []
    Nyckelord :Internal medicine; endocrine tumour; midgut carcinoid; serotonin-producing neuroendocrine carcinoma; prognosis; morphology; tachykinin; connective tissue growth factor; islet autoantigen-2; morphology; carcinoid syndrome; Invärtesmedicin;

    Sammanfattning : In this study, metastasizing serotonin-producing ileocaecal carcinoid tumours (MSPCs) were examined for biological characteristics that could be used to define clinically relevant subgroups within this patient population. Possible targets for new treatment options were also explored. LÄS MER

  7. 10. Aspects of regular long-term endurance exercise in adolescents, with focus on cardiac size and function, hormones, and the immune system

    Författare :Louise Rundqvist; Maria Faresjö; Peter Blomstrand; Katarina Steding-Ehrenborg; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; endurance-trained; cardiac dimension; cardiac systolic function; cardiac diastolic function; growth hormone; immune response; echocardiography; biomarkers; cytokines; chemokines; insulin-like growth factor 1; type 1 diabetes-related autoantigen; proinsulin;

    Sammanfattning : The long-term effects of starting high-intensity training at younger ages are largely unknown. The present studies focused on adolescents who had performed regular endurance exercise for several years at an elite level and compared those subjects with a control group of adolescents of similar age and sex who had not engaged in regular exercise. LÄS MER