Sökning: "atrioventricular conduction"

Visar resultat 11 - 14 av 14 avhandlingar innehållade orden atrioventricular conduction.

  1. 11. The TRIM21/Ro52 E3 ligase and its antibodies in autoimmune disease

    Författare :Aurélie Ambrosi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Patients with the systemic autoimmune diseases systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS) often have autoantibodies against Ro/SSA (composed of the TRIM21/Ro52 and Ro60 antigens) and La/SSB. The biological function of the TRIM21/Ro52 protein itself has remained unknown until its recent description as a tripartite-motif (TRIM) family member and an E3 ligase involved in ubiquitination. LÄS MER

  3. 12. Electromechanical effects and optimization modalities of cardiac resynchronization therapy

    Författare :Cinzia Valzania; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cardiac resynchronization therapy; coronary blood flow; dyssynchrony; echocardiography; exercise; heart failure; hemodynamics; intracardiac electrogram; intracardiac impedance; optimization;

    Sammanfattning : Background and aims: Heart failure is a major health care problem, with high morbidity and mortality rates. In recent years, cardiac resynchronization therapy (CRT) has become an established additive treatment for patients with advanced heart failure, left ventricular (LV) dysfunction, and wide QRS complex. LÄS MER

  4. 13. Life without mitochondrial DNA : studies of transgenic mice

    Författare :Jianming Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :mitochondrial disease; mitochondrial DNA mtDNA ; mitochondrial transcripton factor A Tfam ; cre-loxP; conditional knockout; transgenic; mitochondrial cardiomyopathy; apoptosis;

    Sammanfattning : Mitochondrial DNA (mtDNA) is a closed circular DNA genome that resides in the mitochondrial network. Mutations of mtDNA cause spontaneous and hereditary disorders known as mitochondrial diseases. Mitochondrial transcription factor A (Tfam) is a key factor for transcription of mtDNA in vitro. LÄS MER

  5. 14. Atrial fibrillation : clinical presentation and management, with special emphasis on magnesium therapy

    Författare :Mats Frick; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atrial fibrillation; magnesium; arrhythmias; cardioversion; sotalol;

    Sammanfattning : Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, causing disabling symptoms, risk of thromboembolic events and increased mortality. Some patients with AF are asymptomatic, but to what extent these patients differ from patients with symptoms is unclear. LÄS MER