Sökning: "atherosclerotic morbidity"

Visar resultat 16 - 20 av 29 avhandlingar innehållade orden atherosclerotic morbidity.

  1. 16. Leukocyte-endothelial interactions in arteries in vivo : a new concept in the study of physiology and disease in large blood vessels

    Författare :Einar Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; leukocyte; cell adhesion molecule; chemokine; shear rate; capture; rolling; adhesion; subendothelial; cytokine; artery; intravital; in vivo;

    Sammanfattning : Pathophysiological events in large blood vessels contribute to immense morbidity and mortality in our society. A major clinical problem is a disease known as atherosclerosis. It involves a slow inflammatory deposition of lipid within the walls of large arteries that with time will weaken the arterial wall. LÄS MER

  3. 17. Prevalence and Prognostic Impact of Periodontal Disease and Conventional Risk Factors in Patients with Stable Coronary Heart Disease

    Författare :Ola Vedin; Claes Held; Emil Hagström; Bertil Lindahl; Mai-Lis Hellenius; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary heart disease; Secondary prevention; Prevention; Periodontal Disease; Tooth loss; Risk prediction; Risk factors; Myocardial infarction; Kardiologi; Cardiology;

    Sammanfattning : The purpose of this thesis was to assess the prevalence and management of established cardiovascular (CV) risk factors and the prevalence and influence of self-reported markers (number of teeth and frequency of gum bleeding) of periodontal disease (PD), a less explored CV risk factor, in patients with stable chronic coronary heart disease (CHD).We studied patients from the global STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY (STABILITY) trial (n=15,828), in which patients with stable chronic CHD were randomized to either darapladib or placebo. LÄS MER

  4. 18. Influence of genetics and mechanical properties on large arteries in man

    Författare :Rachel De Basso; Toste Länne; Martin Björck; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Arterial pathology is the major contributor to cardiovascular diseases and mortality. The mechanical properties of arteries are independent factors for cardiovascular disease and mortality, where genetics influence the structure of the arterial wall, which may result in change in arterial stiffness. LÄS MER

  5. 19. Signal transduction in restenosis and myocardial protection by hyperoxia

    Författare :Arno Ruusalepp; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neointima; inflammation; NF-kappaB; preconditioning; MAPK; nitric oxide;

    Sammanfattning : Ischemic heart disease is a major cause of morbidity and mortality in the western world. Revascularization of ischemic myocardium is essential for cell survival, and is performed by thrombolysis, percutaneous transluminal coronary angioplasty (PTCA) and by coronary artery bypass grafting. LÄS MER

  7. 20. Insight into coronary artery ectasia

    Författare :Usama Boles; Michael Y. Henein; Peter Eriksson; Corrado Tamurino; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery ectasia; atherosclerosis; acute coronary syndrome; lipidomic profile; cytokines; prognosis of coronary artery ectasia; kardiologi; Cardiology;

    Sammanfattning : Background:Coronary artery ectasia (CAE) is defined as a diffuse dilatation of the epicardial coronary arteries exceeding 1.5 folds the diameter of the normal adjacent arterial segment and/ or the remaining non-dilated part of the same artery. (1) The incidence of CAE has been variably reported between different nations and ranges between 1. LÄS MER