Sökning: "atherosclerosis"

Visar resultat 21 - 25 av 512 avhandlingar innehållade ordet atherosclerosis.

1. 21. Adiponectin, the metabolic syndrome and atherosclerosis. Observation and intervention studies

   Författare :Carl Johan Behre; Göteborgs universitet; []
   Nyckelord :Adiponectin; inflammation; obesity; weight loss; insulin resistance; the metabolic syndrome; diabetes mellitus type 2; atherosclerosis; ultrasound;

   Sammanfattning : .... LÄS MER

3. 22. Non-invasive ultrasound-based cardiovascular imaging in mouse models of atherosclerosis

   Författare :Julia Grönros; Göteborgs universitet; []
   Nyckelord :atherosclerosis; ultrasound-based imaging; cardiovascular disease; coronary artery; mouse; color Doppler echocardiography; ultrasound biomicroscopy; statin;

   Sammanfattning : Atherosclerosis is a chronic multi-factorial vascular disease. It generally requires large clinical settings and over many years to study the disease progression in man. Genetically modified mouse models of atherosclerosis have dramatically increased research feasibility within this area. LÄS MER

4. 23. A role of CD44 in atherosclerosis? Studies in mice and humans

   Författare :Sara Sjöberg; Göteborgs universitet; []
   Nyckelord :CD44; atherosclerosis; interleukin-6; T cell; mast cell;

   Sammanfattning : Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the cell surface, and soluble CD44 can be detected in blood. LÄS MER

5. 24. Zebrafish models for large-scale genetic screens in dyslipidemia and atherosclerosis : Validation and application

   Författare :Manoj Kumar Bandaru; Marcel den Hoed; Anastasia Emmanouilidou; Ingelsson Erik; Shannon Fisher; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; zebrafish; dyslipidemia; atherosclerosis; genetic screens; high-cholesterol diet; APOE; APOB; LDLR; APOC2; PCSK9; LPAR2; GATAD2A; Medicinsk genetik; Medical Genetics;

   Sammanfattning : Hundreds of loci have been robustly associated with circulating lipids, atherosclerosis and coronary artery disease; but for most loci the causal genes and mechanisms remain uncharacterized. The overall aim of my thesis is to develop and validate novel in vivo model systems that are suitable for high-throughput, image-based genetic screens in coronary artery disease and related traits, and use these model systems to systematically characterize positional candidate genes. LÄS MER

7. 25. Ultrasound evaluation of atherosclerosis and other cardiovascular sources of cerebral embolism

   Författare :Robert Wetterholm; Göteborgs universitet; []
   Nyckelord :stroke; atherosclerosis; aorta; echocardiography; ultrasound; IMT; MES; WHHL;

   Sammanfattning : The search for embolic sources has high priority in patients presenting with suspected cerebral embolism. Non-invasive cardiovascular ultrasound is frequently used to reveal the presence of carotid stenosis and cardiac disorders with embolic potential. LÄS MER