Sökning: "astrocytosis"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet astrocytosis.

  1. 1. Assessment of experimental neurotrauma

    Författare :Ying-Lai Huang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Impulse noise; diffuse brain injury; focal brain injury; closed head injury; NSE; S-100; GFAP; apoptosis; astrocytosis; glutamate; c-JUN; rotational acceleration; CSF;

    Sammanfattning : Model systems of closed head injury are designed to replicate aspects of traumatic brain injury, ischemia and epilepsy in man. The aim of this thesis was to (1) develop sensitive systems enabling analyses of the biochemical reactions, as reflected by leakage of marker compounds to the cerebrospinal fluid (CSF); and (2) develop and assess a new model for closed head injury and associated dynamic changes in the brain cell. LÄS MER

  3. 2. Molecular Characterization of Experimental Traumatic Brain Injury

    Författare :Charlotte Israelsson; Ted Ebendal; Lars Hillered; Anders Lewén; Henrik Hagberg; Uppsala universitet; []
    Nyckelord :Neurosciences; traumatic brain injury; transcripts; GeneChip; chemokine; inflammation; mouse brain; neuroprotection; neuronal injury; neuroregeneration; astrocytosis; Neurovetenskap;

    Sammanfattning : Traumatic brain injury (TBI) is the most common cause of mortality and disability in the younger (.... LÄS MER

  4. 3. Modelling of Diffuse Brain Injury: Combining Methods to Study Possible Links between Transient Intracranial Pressure and Injury

    Författare :Ulrika Krave; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; animal model; astrocytosis; diffuse axonal injury; neurofilaments; diffuse brain injury; rotational acceleration; closed head trauma; rabbit; finite element analysis; intracranial pressure; injury mechanisms;

    Sammanfattning : The objectives of this research are the study of sagittal rotational acceleration induced diffuse brain injury mechanisms. Such injuries are common in vehicle accidents in particular; the consequences range from mild to severe symptoms and may lead to persistent neurological dysfunction. LÄS MER

  5. 4. Multiple amyloid binding sites in Alzheimer brain and their interaction with synaptic and inflammatory mechanisms

    Författare :Ruiqing Ni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer’s disease (AD) is the most common type of dementia. A series of pathophyslogical changes start many years prior to the emergence of clinical symptoms. LÄS MER

  7. 5. A multi-tracer PET approach to study early-onset familial and sporadic Alzheimer's disease

    Författare :Michael Schöll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cumulated scientific evidence suggests that the pathology causing Alzheimer's disease (AD) occurs many years or even decades before memory impairment and other clinical symptoms arise. Tangible and detailed knowledge about different pathological processes, their interactions, and time course is therefore of the essence both for the development of potentially successful treatments and a reliable early diagnosis of this relentless disorder. LÄS MER