Sökning: "astrocyte"

Visar resultat 6 - 10 av 95 avhandlingar innehållade ordet astrocyte.

1. 6. Alpha-Synuclein Oligomers : Cellular Mechanisms and Aspects of Antibody Treatment

   Författare :Gabriel Gustafsson; Martin Ingelsson; Joakim Bergström; Anna Erlandsson; Tiago F Outeiro; Marina Romero-Ramos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s Disease; Alpha-synuclein; Aggregation; Oligomers; Monoclonal Antibody; Glia; Astrocyte; Immunofluorescence; Medicinsk vetenskap; Medical Science;

   Sammanfattning : In Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), aggregated α-synuclein deposit inside cells within the brain. Smaller soluble α-synuclein aggregates, oligomers, are present both intra- and extracellularly. LÄS MER

3. 7. On Multidimensional Dynamic Fluorescence Imaging and Quantitative Image Analysis in Wide-Field Microscopy Applications to Studies of Astroglial Cells

   Författare :Siamak Khatibi; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; volume estimation; astrocyte; calcium wave; intercellular signaling; volumetric image analysis; fluorescence imaging; three-dimensional 3D reconstruction; segmentation;

   Sammanfattning : Modern biological research has benefited from a renaissance in light microscopy, brought about by the convergence of developments in fields as diverse as electronics, optics, molecular biology, computer science, and reagent chemistry. Integration of these has transformed microscopy into a highly useful, dynamic research tool for biology and medicine. LÄS MER

4. 8. Neurogenesis and gliogenesis after focal brain ischemia. Modulation by enriched environment and exercise

   Författare :Mila Komitova; Göteborgs universitet; []
   Nyckelord :astrocyte; hippocampus; neural progenitor cells; neural stem cells; neurogenesis; neurotrophins; rat; regeneration; rehabilitation; stroke;

   Sammanfattning : New neurons are formed from dividing neural stem cells in restricted areas in the adult mammalian brain: the dentate gyrus of the hippocampal formation (DG) and the forebrain subventricular zone (SVZ). New glia also form constitutively and seem to be important for neuronal function. LÄS MER

5. 9. Cellular and Molecular Responses to Traumatic Brain Injury

   Författare :Camilla Lööv; Anna Erlandsson; M. Elly Hol; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic Brain Injury; Astrocyte; Apoptosis; Biomarkers; Ezrin; Actin; Extracellular Proteins; Degradation; Lysosome; Antigen Presentation; Neuroscience; Neurovetenskap; Neurosurgery; Neurokirurgi;

   Sammanfattning : Traumatic brain injury (TBI) is a relatively unknown disease considering the tens of millions of people affected around the world each year. Many TBI patients die from their injuries and survivors often suffer from life-long disabilities. LÄS MER

7. 10. A stargazer's guide to neurodegeneration : Astrocytes' role in the propagation of pathological proteins

   Författare :Tobias Mothes; Anna Erlandsson; Martin Ingelsson; Linn Streubel-Gallasch; Maria Grazia Spillantini; Uppsala universitet; []
   Nyckelord :Alzheimer’s disease; Parkinson’s disease; tauopathies; astrocyte; microglia; neuron; tau; amyloid-β; α-synuclein; accumulation; degradation; inflammation; spreading; seeding.; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by brain accumulation of pathogenic protein aggregates. In the AD brain, amyloid-β (Aβ) and tau form plaques respective tangles, while in the PD brain α-synuclein (α-syn) form Lewy bodies and Lewy neurites. LÄS MER