Sökning: "asthma severity"

Visar resultat 11 - 15 av 51 avhandlingar innehållade orden asthma severity.

1. 11. Peripheral airway function in asthma and cystic fibrosis. Measurements using inert gas washout methods

   Författare :Henrik Ljungberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acinar; adults; airway hyperresponsiveness; asthma; children; conductive; functional residual capacity; gas trapping; inert gas washout; infants; peripheral airways; plethysmography; respiratory function tests; ventilation inhomogeneity;

   Sammanfattning : It is increasingly recognised that asthma and cystic fibrosis (CF) frequently involves the peripheral airways. Characteristic features of abnormal peripheral airway function are uneven ventilation distribution and increased gas trapping. LÄS MER

3. 12. On airway host defence during allergic inflammation

   Författare :Anele Gela; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

   Sammanfattning : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. LÄS MER

4. 13. Array-based identification of disease-associated proteins

   Författare :Maria Mikus; Peter Nilsson; Jochen M. Schwenk; Ina Schuppe-Koistinen; Dolores Cahill; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; Antibody array; Antigen array; Amyotrophic lateral sclerosis; Asthma; Atopic dermatitis; Biomarker discovery; Drug-induced liver injury; Microarray; Plasma; Protein microarray; Protein profiling; Serum; Suspension bead array; Bioteknologi; Biotechnology;

   Sammanfattning : To increase our understanding of the human body in both health and disease, proteins can be studied in samples such as plasma and serum to provide a molecular profile of the physiological status. In the work presented in this thesis, array-based methods were used to study associations of protein and autoantibody profiles with disease. LÄS MER

5. 14. The asthmatic airway response – effects on physiology and biomarkers

   Författare :Henning Stenberg; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :Asthma; Exhaled breath temperature; Exercise; Allergen challenge; Small airways; Airway provocations; Spirometry; Impulse oscillometry; Inert gas washout; Body plethysmography; Club cell protein CC16 ;

   Sammanfattning : Asthma is a common airway inflammatory disease, associated with a variable degree of airway obstruction. It is a heterogeneous condition with large variations in severity and clinical presentation. Moreover, disease activity can vary from time to time. Taken together, these factors make the diagnosis, monitoring and treatment of asthma challenging. LÄS MER

7. 15. Phenotyping of severe asthma in a clinical context

   Författare :Valentyna Yasinska; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Severe asthma is a chronic heterogeneous inflammatory disease characterized by several clinical phenotypes and molecular endotypes. Although it affects a relatively small proportion of the asthma population (approximately 4%-10%), with an even smaller proportion of these having severe uncontrolled eosinophilic asthma, it accounts for > 50% of the costs attributed to the disease. LÄS MER