Sökning: "asthma severity"
Visar resultat 11 - 15 av 51 avhandlingar innehållade orden asthma severity.
11. Peripheral airway function in asthma and cystic fibrosis. Measurements using inert gas washout methods
Sammanfattning : It is increasingly recognised that asthma and cystic fibrosis (CF) frequently involves the peripheral airways. Characteristic features of abnormal peripheral airway function are uneven ventilation distribution and increased gas trapping. LÄS MER
12. On airway host defence during allergic inflammation
Sammanfattning : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. LÄS MER
13. Array-based identification of disease-associated proteins
Sammanfattning : To increase our understanding of the human body in both health and disease, proteins can be studied in samples such as plasma and serum to provide a molecular profile of the physiological status. In the work presented in this thesis, array-based methods were used to study associations of protein and autoantibody profiles with disease. LÄS MER
14. The asthmatic airway response – effects on physiology and biomarkers
Sammanfattning : Asthma is a common airway inflammatory disease, associated with a variable degree of airway obstruction. It is a heterogeneous condition with large variations in severity and clinical presentation. Moreover, disease activity can vary from time to time. Taken together, these factors make the diagnosis, monitoring and treatment of asthma challenging. LÄS MER
15. Phenotyping of severe asthma in a clinical context
Sammanfattning : Severe asthma is a chronic heterogeneous inflammatory disease characterized by several clinical phenotypes and molecular endotypes. Although it affects a relatively small proportion of the asthma population (approximately 4%-10%), with an even smaller proportion of these having severe uncontrolled eosinophilic asthma, it accounts for > 50% of the costs attributed to the disease. LÄS MER