Sökning: "astakine"

Hittade 4 avhandlingar innehållade ordet astakine.

  1. 1. Hematopoiesis in a Crustacean

    Författare :Xionghui Lin; Irene Söderhäll; Kenneth Söderhäll; Michael J. Williams; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; astakine; cytokine; hematopoiesis; prokineticin; transglutaminase; ATP synthase; innate immunity; apoptosis; Immunology; Immunologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Hemocytes (blood cells) play an important role in the immune response in invertebrates, and thus the regulation of hemocyte homeostasis (hematopoiesis) is essential for the host survival against pathogens. Astakine 1, a homologue to vertebrate prokineticins, was first identified in the freshwater crayfish Pacifastacus leniusculus as a cytokine, and was found to be necessary for new hemocyte synthesis and release in vivo, and also to induce spreading and proliferation of Hematopoietic tissue cells (Hpt cells, precursor of hemocytes) in vitro. LÄS MER

  3. 2. Melanization and Hemocyte Homeostasis  in the Freshwater Crayfish, Pacifastacus leniusculus

    Författare :Chadanat Noonin; Irene Söderhäll; Kenneth Söderhäll; Smith Valerie; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; melanization; prophenoloxidase; caspase; hematopoiesis; thymosin; astakine; circadian rhythm; reactive oxygen species; tyrosinase; prokineticin;

    Sammanfattning : Blood cells or hemocytes play important roles in immunity. They are a major source of many immune-related molecules such as antibodies in adaptive immunity of vertebrates and prophenoloxidase (proPO) in invertebrates. LÄS MER

  4. 3. Hematopoiesis, Kazal Inhibitors and Crustins in a Crustacean

    Författare :Young-A Kim; Kenneth Soderhall; Irene Soderhall; Shun-ichiro Kawabata; Uppsala universitet; []
    Nyckelord :Biochemistry; innate immunity; cytokine; hematopoietic tissue; ATP synthase β subunit; Kazal; antibacterial peptides; Biokemi;

    Sammanfattning : Hemocytes are important as storage and producers of proteins of the innate immune defence, as well as actors of the cellular immune response. Therefore the hematopoietic process is critical for survival of most invertebrates. LÄS MER

  5. 4. White Spot Syndrome Virus Interaction with a Freshwater Crayfish

    Författare :Pikul Jiravanichpaisal; Kenneth Söderhäll; Irene Söderhäll; Ellen Kauschke; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; WSSV; crayfish; hematopoietic tissue; cytokine; innate immunity; hemocytes; Biologi; Biology; Biologi;

    Sammanfattning : Viruses are very abundant in water and hence diseases caused by viruses are common in marine organisms. These diseases create great problems for the commercial farming of crustaceans and mussels. LÄS MER