Sökning: "articular cartilage"

Visar resultat 6 - 10 av 67 avhandlingar innehållade orden articular cartilage.

  1. 6. Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan content in articular cartilage

    Författare :Carl Johan Tiderius; Ortopedi - klinisk och molekylär osteoporosforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; exercise; osteoarthritis; anterior cruciate ligament; glycosaminoglycan; MRI; cartilage; dGEMRIC; knee;

    Sammanfattning : Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. LÄS MER

  3. 7. Molecular regulators in cartilage and bone formation

    Författare :Thomas Engstrand; Uppsala universitet; []
    Nyckelord :Medical sciences; cartilage; bone; TGF-beta; BMP; noggin; gene therapy; gene targeting; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Cartilage functions as a scaffold for bone formation during development. This process, endochondral ossification, is regulated by systemic hormones and local growth factors. LÄS MER

  4. 8. Ions in models of articular cartilage : The importance of electrostatic interactions for transport and equilibrium distribution

    Författare :Jenny Algotsson; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; articular cartilage; Donnan equilibrium; diffusion; MRI; Monte Carlo simulations; dGEMRIC;

    Sammanfattning : Osteoarthritis (OA) is a degenerative disease that affects articular cartilage, which covers the surfaces of the bones in synovial joints. At later stages the disease can result in major loss of articular cartilage and thus lead to major disability. LÄS MER

  5. 9. Influences of in vivo and in vitro loading on the proteoglycan synthesis of articular cartilage chondrocytes

    Författare :Mikko Lammi; Markku Tammi; Jukka Finne; Tim Hardingham; Finland Kuopio University of Kuopio Department of Anatomy; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Articular cartilage; proteoglycans; loading; stress; hydrostatic pressure; biokemi; Biochemistry; cell research; cellforskning; molekylärbiologi; Molecular Biology; ortopedi; Orthopaedics;

    Sammanfattning : In this study, the biosynthesis of proteoglycans (PGs) was examined in articular cartilage of canine hip joint after long-distance running experiment and in bovine chondrocyte cultures during in vitro loading with hydrostatic pressure. In addition, new assays were developed for more sensitive quantitation of glycosaminoglycans (GAGs) and PGs. LÄS MER

  7. 10. Mechanics and Growth of Articular Cartilage Around a Localized Metal Implant

    Författare :Krishnagoud Manda; Anders Eriksson; Nico Verdonschot; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; finite element analysis; articular cartilage defects; growth; knee; focal knee resurfacing; metal implant; poroelastic; porohyperelastic; biphasic;

    Sammanfattning : Articular cartilage is a specialized connective soft tissue that resides on the ends of long-bones, and transfers the load smoothly between the bones in diarthrodial joints by providing almost frictionless, wear resistant sliding surfaces during joint articulation. Focal chondral or osteochondral defects in articular cartilage are common and show limited capacity for biological repair. LÄS MER