Sökning: "artemisinin-based combination therapies ACTs"

Hittade 4 avhandlingar innehållade orden artemisinin-based combination therapies ACTs.

  1. 1. Efficacy of artemisinin based combination therapy and effectiveness of rapid diagnostic test for management of patients with plasmodium falciparum malaria in Zanzibar

    Författare :Mwinyi I Msellem; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum malaria; artemisinin-based combination therapies ACTs ; efficacy; rapid diagnostic test RDT ; Zanzibar;

    Sammanfattning : Background: Due to rapid spread of antimalarial drug resistance to Plasmodium falciparum malaria many African countries have recently changed their first-line treatment policy to artemisinin-based combination therapy (ACT). Zanzibar was one of the first regions in Africa to implement ACT free of charge to all age groups through public health facilities in 2003. LÄS MER

  3. 2. In vitro and in vivo studies of artemisinin endoperoxides

    Författare :Therese Ericsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Artemisinin; Artesunate; Breast cancer; Cytochrome P450; Dihydroartemisinin; Inhibition; LC-MS MS; Pharmacokinetics; Plasma; Saliva;

    Sammanfattning : Artemisinin and its semi-synthetic derivatives (eg. Artemether/ARM, artesunate/ARS, dihydroartemisinin/DHA) play an important role in combating malaria, and treatments containing an artemisinin derivative (artemisinin-based combination therapies, ACTs) are today the standard treatment worldwide for Plasmodium falciparum malaria. LÄS MER

  4. 3. Targeting malaria elimination : an assessment of malaria control interventions for children in Zanzibar

    Författare :Netta Beer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Zanzibar;

    Sammanfattning : Background: After decades of neglect, a renewed global focus on malaria was initiated in the 90s, followed by global financial support in the early 2000s. Zanzibar has been in the forefront of these renewed efforts: Case management and vector-control interventions have been implemented and scaled-up rapidly, resulting in markedly reduced malaria transmission and the targeting of malaria elimination. LÄS MER

  5. 4. Molecular methods in malaria control in the era of pre-elimination

    Författare :Ulrika Morris; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Increased funding combined with effective malaria control methods for prevention, diagnosis, and treatment, has resulted in a 30% reduction of the global malaria burden over the last decade. As malaria prevalence declines in areas of successful malaria control, the proportion of subpatent infections that fall below the detection level of malaria rapid diagnostic tests (RDTs) and microscopy increases. LÄS MER