Sökning: "arefalk"

Hittade 2 avhandlingar innehållade ordet arefalk.

  1. 1. Smokeless Tobacco (Snus) and Cardiovascular Disease : Associations with Heart Failure and Prognosis after Myocardial Infarction

    Författare :Gabriel Arefalk; Johan Sundström; Martin Holzmann; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Snus; smokeless tobacco; nicotine; cardiovascular disease; heart failure; myocardial infarction; mortality; prognosis; epidemiology; Epidemiologi; Epidemiology;

    Sammanfattning : Previous investigations of snus use (oral moist snuff, a Swedish form of smokeless tobacco) and cardiovascular disease have generally focused on atherosclerotic events such as myocardial infarction and stroke, likely because smoking is such a well-established risk factor for atherosclerotic disease. Smokeless administration of tobacco circumvents most of the atherogenic effects of the combusted products from smoked tobacco, but it is possible that the potent autonomic and hemodynamic effects of snus and nicotine per se are detrimental for cardiovascular tissues. LÄS MER

  2. 2. New Methods for the Synthesis of 3-Substituted 1-Indanones : A Palladium-Catalyzed Approach

    Författare :Anna Arefalk; Anders Hallberg; Mats Larhed; Juan Carlos Carretero; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Heck; palladium; indanone; annulation; microwave heating; triflate; sulfinyl imine; HIV-1 protease inhibitor; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : In medicinal chemistry, there is a constant need for new preparative methods, both to make the synthesis process more effective, and to increase the accessibility to a wide variety of compounds. A number of different approaches can be used to attain these goals. LÄS MER