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Visar resultat 11 - 15 av 7930 avhandlingar innehållade ordet area.

  1. 11. Immunological aspects on cystic fibrosis lung disease

    Författare :Malin Carlsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunology; serology; pyocyanin; mannan binding lectin; Pseudomonas aeruginosa; ANCA; Cystic fibrosis; bactericidal permeability increasing protein; Immunologi; serologi;

    Sammanfattning : In cystic fibrosis (CF) colonization of the airways with Pseudomonas aeruginosa is a major cause of deterioration and death. Host defence fails to clear the invading bacteria, which results in a chronic destructive inflammatory process. LÄS MER

  3. 12. Plasminogen and protein PAM: Interactions between streptococcal surface proteins and the human fibrinolytic system

    Författare :Annika Carlsson Wistedt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; M protein; streptokinase; kringles; plasmin; Streptococcus pyogenes; plasminogen; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Pathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. LÄS MER

  4. 13. Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions

    Författare :Cecilia Cederfur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; glycoprotein; asthma; bronchoalveolar lavage; galectin binding protein; galectin ligand; galectin; serum;

    Sammanfattning : Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. LÄS MER

  5. 14. Systemic and local regulation of experimental arthritis by IFN-α, dendritic cells and uridine

    Författare :Sudeep Chenna Narendra; Mattias Magnusson; Srinivas Uppugunduri; Alf Kastbom; Natacha Bessis; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In this thesis, we have studied the immunological processes of joint inflammation that may be targets for future treatment of patients with arthritis. We focus on the immune-modulating properties of interferon-α (IFN-α) and uridine in experimental arthritis. LÄS MER

  7. 15. Neutrophil recruitment in periodontal disease

    Författare :Agnes Dahlstrand Rudin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophil; periodontitis; P. gingivalis; F. nucleatum; SCFA; FFAR2; CD177; A1AT;

    Sammanfattning : Neutrophils are the first immune cells to arrive in infected or injured tissues, where they engulf microbes and clean up cell debris. Periodontitis is one of the typical symptoms of both neutropenia and defect neutrophil functionality, suggesting an important role for these cells in maintenance of periodontal health. LÄS MER