Sökning: "archival samples"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden archival samples.

  1. 1. Usefulness of archival biobank samples for genetic epidemiologic studies

    Författare :Malin Sjöholm; Malmö Klinisk mikrobiologi; []
    Nyckelord :formailn-fixed paraffin-embedded tissue; biobank; serum; dried blood spots; plasma; archival samples;

    Sammanfattning : Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. LÄS MER

  3. 2. The use of formalin fixed paraffin embedded tissue and global gene expression profiling for increased understanding of squamous cell carcinoma of the tongue

    Författare :Rentoft Matilda; Karin Nylander; Michael Prystowsky; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SCCHN; tongue; microarray; DASL; FFPE; archival; mRNA; miRNA; patologi; Pathology;

    Sammanfattning : Head and neck cancer is the 6th most common malignancy worldwide, with tumours of the tongue being one of the most prevalent sites. Despite advances in surgery and radiotherapy, the five-year survival has not changed during the last decades and remains at approximately 50%. LÄS MER

  4. 3. Cervical carcinoma in Kampala, Uganda, and the relationship with human immunodeficiency virus and human papillomavirus infections

    Författare :Michael Odida; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HPV; Human Papillomaviruses; women; HIV; Uganda; invasive cervical cancer;

    Sammanfattning : Introduction: Cervical carcinoma is the commonest tumour in Ugandan women. However, very little is known in the Ugandan population about HPV types associated with invasive cervical cancer, the relative risk of cervical cancer associated with different HPV types, and whether the risk of cervical cancer associated with HPV infection is modified by HIV infection. LÄS MER

  5. 4. Med kant av guld och silver... : En studie av knypplade bårder och uddar av metall 1550-1640

    Författare :Lena Dahrén; Margareta Nockert; Maths Isacson; Johan Knutsson; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Bobbin lace; gold; silver; edgings; borders; ecclesiastic textiles; dress costume; portrait; Knyppling; guld; silver; liturgiska textilier; dräkt; porträtt; handel; Art; Konstvetenskap; Textile Studies; Textilvetenskap;

    Sammanfattning :  The study examines bobbin-made borders and edgings in gold and silver during the period 1550-1640. The aim of the thesis is to study the technique of bobbin made lace and to place it in a historical, social and economic context. LÄS MER

  7. 5. Molecular markers reflecting malignant transformation and tumor progression

    Författare :Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

    Sammanfattning : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. LÄS MER