Sökning: "apoptosis of t cells"

Visar resultat 16 - 20 av 240 avhandlingar innehållade orden apoptosis of t cells.

  1. 16. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis

    Författare :Sofia Edlund; Pontus Aspenström; Maréne Landström; Tommy Andersson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-beta; cytoskeleton; GTPases; mitogen-activated protein kinase kinase 3; TGF-beta-activated kinase 1; Apoptosis; Smad7; beta-catenin; p38 MAPK; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. LÄS MER

  3. 17. Eosinophils, their progenitors and T helper cells in allergic airway inflammation

    Författare :You Lu; Göteborgs universitet; []
    Nyckelord :eosinophils; eosinophil progenitors; T helper cells; Th2 cells; IL-33; migration; Asthma;

    Sammanfattning : Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and treatment responses in allergic asthma. LÄS MER

  4. 18. Molecular Monitoring of Chronic Myeloid Leukemia Treated with Imatinib Mesylate

    Författare :Yuan Wei; Göteborgs universitet; []
    Nyckelord :CML; imatinib; BCR-ABL; apoptosis; mutation; T-lymphocyte;

    Sammanfattning : The BCR-ABL fusion gene product is a constitutively activated tyrosine kinase, which is fundamental in the pathogenesis of chronic myeloid leukemia (CML). Imatinib mesylate (imatinib, Glivec® or Gleevec®), a small molecule inhibitor of the BCR-ABL tyrosine kinase, is now the first-line treatment for all newly diagnosed chronic phase CML patients. LÄS MER

  5. 19. Maturation of humoral immune responses : Studies on the effects of antigen type, apoptosis and age

    Författare :Karin Lindroth; Carmen Fernández; Kenneth G.C. Smith; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; B cell; humoral immune response; Immunology; Immunologi;

    Sammanfattning : The humoral immune response is dependent on the formation of antibodies. Antibodies are produced by terminally differentiated B cells, plasma cells. Plasma cells are generated either directly from antigen challenged B cells, memory cells or from cells that have undergone the germinal center (GC) reaction. LÄS MER

  7. 20. In vitro studies on the potential immunosuppressive and antitumor effects of antidepressants : induction of apoptosis in human T-cells and a myeloid leukemia cell line

    Författare :Zhenlei Xia; Tom Cotter; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : Antidepressants are widely used in treating depressive disorders. It has been demonstrated that several components of the immune system may be activated in the acute clinical stage of major depression and that such activation may play a role in the onset of depressive symptoms. LÄS MER