Sökning: "apolipoprotein B"

Visar resultat 6 - 10 av 67 avhandlingar innehållade orden apolipoprotein B.

  1. 6. Growth hormone and PPARa in the regulation of lipoprotein metabolism

    Författare :Daniel Lindén; Göteborgs universitet; []
    Nyckelord :growth hormone; insulin; fatty acids; PPARa; apolipoprotein B; VLDL; mRNA editing;

    Sammanfattning : In humans, apolipoprotein B (apoB)-100 is produced in the liver and apoB-48 is formed in the intestine. In the rat, however, the two forms of apoB are produced in the liver, leading to the formation of VLDL consisting of either apoB-48 or apoB-100. LÄS MER

  3. 7. Myocardial metabolism in experimental infarction and heart failure

    Författare :Truls Råmunddal; Göteborgs universitet; []
    Nyckelord :Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Sammanfattning : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. LÄS MER

  4. 8. The assembly and secretion of ApoB containing lipoproteins

    Författare :Pia Stillemark; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apolipoprotein B; lipoprotein; VLDL; microsomal triglyceride transfer protein; chaperone;

    Sammanfattning : Increased levels of cholesterol and triglycerides in the blood are important risk factors for the development of premature atherosclerosis and its complications such as coronary-heart diseases, stroke and peripheral vascular diseases. These diseases are the major causes of death in Europe, USA and part of Asia. LÄS MER

  5. 9. Homocysteine and its determinants in relation to cardiovascular risk factors and myocardial infarction

    Författare :Elisabet Söderström; Johan Hultdin; Torbjörn K. Nilsson; Anders Larsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Homocysteine; folate; myocardial infarction; apolipoprotein; risk factors; cotinine; nicotine; tobacco; CTH; MTHFR; renal insufficiency; glomerular filtration rate; creatinine; cystatin C; shrunken pore syndrome; epidemiology; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Background: Globally, cardiovascular diseases (CVD), including myocardial infarction (MI) and stroke, are the leading cause of illness and death and constitute a significant part of the disease burden in Sweden and Western Europe. Age, hypertension, smoking, obesity, dyslipoproteinemia, diabetes, and impaired renal function are considered established risk factors for CVD. LÄS MER

  7. 10. Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models

    Författare :Maria Skoog; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Lipid; ACTH; Apolipoprotein-B; Cholesterol; Human; Rat; Rabbit; Medicin människa och djur ;

    Sammanfattning : Abstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. LÄS MER