Sökning: "aortic ring"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden aortic ring.

1. 1. Methodological studies applying new techniques for evaluation of arterial function

   Författare :Margareta Ring; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Atherosclerotic cardiovascular disease is the most common cause of death in the Western world today. Atherosclerosis in the arterial wall is related to aging and the inflammatory and calcification processes, and is influenced by risk factors such as smoking, male gender, diabetes, hypertension, obesity, stress, inactivity, hyperlipidemia, and genetic factors. LÄS MER

3. 2. On the stimulatory effect of microglial cells on angiogenesis

   Författare :Simin Rymo; Göteborgs universitet; []
   Nyckelord :microglia; angiogenesis; aortic ring;

   Sammanfattning : ABSTRACT Angiogenesis, the process by which new vessels sprout from pre-existing vessels, is fundamental to development, tissue growth and repair. The main aim of this thesis was to investigate the role of microglia on angiogenesis. We adapted the rat ex vivo/in vitro aortic ring model to the mouse in a 3-D culture system. LÄS MER

4. 3. Functional characterization of pro-angiogenic neutrophils

   Författare :Jalal Lomei; Mia Phillipson; Gustaf Christoffersson; Johan Kreuger; Lars Olaf Cardell; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; leukocytes; neutrophils; pro-angiogenic neutrophils; islets transplantation; intravital microscopy; aortic ring assay; phagocytosis; ROS production; hypoxia; vascular permeability; neutrophil recruitment; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste products from cell metabolism. Angiogenesis, formation of new blood vessels by sprouting from pre-existing vessels, is one of the main mechanisms involved in blood vessel formation. LÄS MER

5. 4. Amyloids here, amyloids there…What’s wrong with them?

   Författare :Anna Gharibyan; Ludmilla Morozova-Roche; Tuomas Knowels; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloids; oligomers; fibrils; cytotoxicity; Alzheimer s disease; Aortic stenosis; S100A9; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Amyloid formation is inherent property of proteins which under certain circumstances can become a pathologic feature of a group of diseases called amyloidosis. There are about 30 known human amyloidosis and more than 27 identified proteins involved in these pathologies. LÄS MER

7. 5. Investigation of the origin of the coronary artery calcification process and its relationship to the atherosclerotic cardiovascular disease

   Författare :George Koulaouzidis; Michael Henein; Katrine Åhlström Riklund; Jan Engvall; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery calcification; ethnicity; South Asians; Caucasians; reproducibility; aortic valve calcification; mitral valve calcification; family history of coronary artery disease; natural history; coronary artery calcium score; meta-analysis;

   Sammanfattning : The objectives of this thesis are: a) To examine racial/ethnic differences in coronary artery calcification (CAC) and CAD, between symptomatic South Asians and Caucasians, matched for age, gender and conventional cardiovascular risk factors, b) To assess, using a meta-analysis model, the natural history of and stability of measurements of coronary artery calcium scoring (CACs) based on data collected from two large published trials: St Francis and EBEAT, c) To investigate the prevalence of coronary artery calcification in individuals with CT evidence for AVC, mitral valve calcification (MAC) or of both of them (AVC+MAC), d) To assess any potential association between premature CAD (.. LÄS MER