Sökning: "antiviral response"

Visar resultat 6 - 10 av 96 avhandlingar innehållade orden antiviral response.

  1. 6. Resistance to antiviral drugs in HIV and HBV

    Författare :Anna Lindström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HBV; drug-resistance; Sanger sequencing; pyrosequencing;

    Sammanfattning : Development of resistance to antiviral drugs is a major problem in treatment of several viral infections including human immunodeficiency type 1 (HIV-1) and hepatitis B virus (HBV). Resistance may be the primary reason for treatment failure, but may also develop secondary to problems with adherence or pharmacokinetics. LÄS MER

  3. 7. HIV-induced humoral immune response with specific relevance to IgA

    Författare :Pia Skott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; secretory lgA; neutralizing antibodies; mucosal immunity;

    Sammanfattning : Human Immunodeficiency Virus (HIV) transmission occurs primarily after hetero- and homosexual contact and across mucosal surfaces. The immune response in mucosal tissues is typified by secretory immunoglobulin A (SIgA), which is the predominant lg class in human external secretions. LÄS MER

  4. 8. Anti-herpes simplex virus activities of sulfomannan oligosaccharide PI-88 and disulfated cyclitols

    Författare :Maria Ekblad; Göteborgs universitet; []
    Nyckelord :herpes simplex virus; antiviral drugs; viral glycoproteins; heparan sulfate mimetic; PI-88;

    Sammanfattning : Herpes simplex virus (HSV) initiates invasion of human cells by binding to the cell surface heparan sulfate (HS) glycosaminoglycan chains. This step is mediated by the viral envelope glycoproteins gC and/or gB. LÄS MER

  5. 9. Interfering with interferons : interplay between SARS-CoV-2 and interferon response

    Författare :Xi Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused the coronavirus disease 2019 (COVID-19) pandemic, which has been an ongoing global health crisis. At the beginning of the pandemic, all the efforts were directed toward understanding the pathogenesis of the virus. LÄS MER

  7. 10. Interferons in antiviral defense and autoimmunity : focus on type 1 diabetes

    Författare :Monica Hultcrantz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; interferons; islets of Langerhans; Coxsackievirus; nonobese diabetic mouse;

    Sammanfattning : Type 1 diabetes (T1D) is a disease characterized by the loss of insulin producing beta-cells in the pancreatic islets of Langerhans. Interferons (IFNs), produced by immune cells and infected parenchymal cells, may be protective or damaging in the pathogenesis of T1D. LÄS MER