Sökning: "antiviral response"

Visar resultat 11 - 15 av 96 avhandlingar innehållade orden antiviral response.

  1. 11. Crimean-Congo hemorrhagic fever virus : interferon-induced antiviral mechanisms and immune evasion strategies

    Författare :Ida Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Bunyaviridae family is the largest virus family consisting of more than 350 viruses. Despite the increasing knowledge regarding the biology of members of this family, little is known about Crimean-Congo hemorrhagic fever virus (CCHFV), a virus classified within the Nairovirus genus and the causative agent of a severe hemorrhagic fever in humans with high mortality. LÄS MER

  3. 12. Biology of HIV transmission and antiviral mucosal immunity in the female genital tract

    Författare :Pauline Levinson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus (HIV) is primarily transmitted through heterosexual intercourse and women in Sub-Saharan Africa are disproportionately affected. Correlates of protective immunity and mucosal factors influencing sexual HIV transmission need to be identified as they may serve as critical targets for HIV intervention. LÄS MER

  4. 13. Human cytomegalovirus : development of resistance to antiviral drugs and mechanisms of NK-cell evasion

    Författare :Mehrdad Mousavi-Jazi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human cytomegalovirus (HCMV), a member of the herpesviridae, is ubiquitous and causes persistent infections mostly without any clinical symptoms. However, HCMV infection is a major cause of morbidity and mortality among immunocompromised patients, especially transplant recipients and patients with AIDS. LÄS MER

  5. 14. A battle between host and pathogen : the innate immune response and enterovirus evasion strategies

    Författare :Katharina Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and pancreatitis. Infections with Coxsackieviruses have also been implicated in the pathogenesis of type 1 diabetes (T1D). LÄS MER

  7. 15. Emerging role of RIG-I-like receptors in antiviral innate immunity in airway structural cells

    Författare :Jenny Calvén; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Respiratory viral infections, especially involving rhinovirus, are main triggers of exacerbations of asthma and COPD. These severe conditions are a great burden to both the individual and society and currently lack effective treatments. LÄS MER