Sökning: "antithrombin"

Visar resultat 21 - 25 av 29 avhandlingar innehållade ordet antithrombin.

  1. 21. The effect of thrombin inhibitors on coagulation activity and generation of activated protein C

    Författare :Rikard Linder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The direct thrombin inhibitor inogatran was, in the TRIM trial (n=1209), compared with unfractionated heparin (UFH) concerning the effect on cardiovascular end-points in unstable coronary artery disease. The results in TRIM demonstrated a trend towards a benefit for UFH during the treatment phase, which was reduced after drug withdrawal. LÄS MER

  3. 22. Reproductive aspects of the protein C system in women

    Författare :Margareta Wramsby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hypercoagulation; Factor V Leiden; APC resistance; Protein C inhibitor; Recurrent abortions; Menstrual cycle; Pregnancy; Controlled ovarian hyperstimulation.;

    Sammanfattning : Of great importance to the reproductive system in women are the activating and inhibiting factors which maintain haemostatic balance. These play a prominent role in the prevention of abnormal bleeding, at ovulation as well as during menstruation, pregnancy and delivery. The coagulation cascade is primarily down regulated by the protein C system. LÄS MER

  4. 23. Surgery for acute coronary syndromes

    Författare :Staffan Bjessmo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :acute coronary syndromes; coronary artery bypass surgery; mortality; acute myocardial infarction; troponin-T; blood loss; coagulation system activity;

    Sammanfattning : This thesis comprises two observational retrospective and three prospective studies of patients with acute coronary syndromes undergoing urgent coronary bypass surgery. All included patients underwent coronary artery bypass surgery at the Karolinska Hospital in Stockholm. LÄS MER

  5. 24. Hypercoagulation in preeclampsia : implications for maternal health and fetal growth

    Författare :Shu He; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension, proteinuria, oedema and hypercoagulation. Damage in organs, such as the liver and kidney, is harmful to the maternal health. Impairments in placental function cause intrauterine growth retardation (IUGR). LÄS MER

  7. 25. Effects of combined oral contraceptives on hemostasis and biochemical risk indicators for venous thromboembolism and atherothrombosis

    Författare :Marianne van Rooijen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Combined oral contraceptives; emergency contraception; menstrual cycle; ethinylestradiol; levonorgestrel; desogestrel; lipoproteins; hemostasis; risk indicators; APC resistance; SHBG;

    Sammanfattning : Combined oral contraceptives (COCs) are one of the most common contraceptive methods in the world. Already a few years after their introduction, in the early 1960s, case reports were published showing associations between use of COCs and venous and arterial thromboembolism. LÄS MER