Sökning: "antisense DNA"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden antisense DNA.

  1. 1. Antisense technology and bone resorption

    Författare :Marie Suzanne Westberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antisense DNA; carbonic anhydrase II; vacuolar H -ATPase; bone resorption; ostoclast;

    Sammanfattning : .... LÄS MER

  3. 2. Self-assembly Strategies for Functional DNA Nanostructures

    Författare :John Tumpane; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbon nanotube; polarised spectroscopy; nanotechnology; self-assembly; orientation; lipid membrane; gel electrophoresis; DNA;

    Sammanfattning : The technological revolution of the twentieth century was famously subject to Moore’s law which related the rate of growth to the ability to scale-down the size of the components – size matters. Several decades later we are, however, approaching the limit of what is possible with silicon wafers. LÄS MER

  4. 3. Inflammatogenic properties of endogenous DNA

    Författare :Shahin Hajizadeh; Göteborgs universitet; []
    Nyckelord :Inflammation; mtDNA; oxidized DNA; SF; CSF; RA; dementia;

    Sammanfattning : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. LÄS MER

  5. 4. Making Sense of Antisense

    Författare :Johan Reimegård; Gerhart Wagner; Hanah Margalit; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sRNA; miRNA; RNA; target prediction; SOLiD siRNA; E.coli; D.discoideum; Biology; Biologi; Bioinformatics; Bioinformatik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : RNA is a highly versatile molecule with functions that span from being a messenger in the transfer from DNA to protein, a catalytic molecule important for key processes in the cell to a regulator of gene expression. The post-genomic era and the use of new techniques to sequence RNAs have dramatically increased the number of regulatory RNAs during the last decade. LÄS MER

  7. 5. Gene Expression and DNA Methylation in Acute Lymphoblastic Leukemia

    Författare :Jessica Nordlund; Syvänen Ann-Christine; Xavier Estivill; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Digital gene expression; Allele-specific gene expression; DNA methylation; Epigenetics; Acute lymphoblastic leukemia; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Pediatric acute lymphoblastic leukemia (ALL) is the most common malignancy in children, which results from the malignant transformation of progenitor cells in the bone marrow into leukemic cells. The precise mechanisms for this transformation are not well defined, however recent studies suggest that aberrant regulation of gene expression or DNA methylation may play an important role. LÄS MER