Sökning: "antiretroviral resistance"

Visar resultat 1 - 5 av 49 avhandlingar innehållade orden antiretroviral resistance.

  1. 1. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects

    Författare :Erik Sörstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; transient viremia; viral blip; nucleoside transcriptase inhibitor resistance; dolutegravir; baseline viral load; HIV RNA; virological failure;

    Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER

  3. 2. Antiretroviral Treatment at Ethiopian Health Centers

    Författare :Anton Reepalu; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In 2017,for the first time, more than half of all people living with HIV (PLHIV) had access to antiretroviral treatment (ART). This expansion of ART has in part been achieved through decentralization of HIV care in resource-limited settings. There, many PLHIV now receive care at ART clinics integrated within the primary health care system. LÄS MER

  4. 3. The HIV-1 epidemic in Ethiopia – transmission patterns, antiretroviral drug resistance and treatment outcomes

    Författare :Dawit Assefa; Malmö Klinisk virologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV drug resistance HIVDR ; Phylodynamics; Phylogenetic; Molecular epidemology; transmitted HIVDR; acquired HIVDR; pre-treatment HIVDR; Integrase strand transfer inhibitors INSTI ; Ethiopia; antiretroviral therapy;

    Sammanfattning : A comprehensive understanding of local HIV epidemiology is essential for monitoring transmission, designing, implementing, and evaluating HIV intervention strategies. In paper I, we used a total of 1276 HIV-1 subtype C pol sequences and employed state-of-art phylogenetic and phylodynamic tools to describe the molecular epidemiology of HIV in Ethiopia. LÄS MER

  5. 4. Resistance to antiviral drugs in HIV and HBV

    Författare :Anna Lindström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HBV; drug-resistance; Sanger sequencing; pyrosequencing;

    Sammanfattning : Development of resistance to antiviral drugs is a major problem in treatment of several viral infections including human immunodeficiency type 1 (HIV-1) and hepatitis B virus (HBV). Resistance may be the primary reason for treatment failure, but may also develop secondary to problems with adherence or pharmacokinetics. LÄS MER

  7. 5. Antiretroviral treatment outcome and molecular epidemiology of HIV-1 subtype C drug resistance in Ethiopia

    Författare :Nigus Fikrie Telele; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Over the last decade, antiretroviral therapy (ART) has been rolled out in Ethiopia at a large scale. However, the outcome and aspects of drug resistance have been poorly studied at the national level. Also, the epidemic has been reported to be dominated by HIV-1 subtype C (HIV-1C), but this has not been verified at a nationwide level. LÄS MER