Sökning: "antimicrobial"

Visar resultat 21 - 25 av 385 avhandlingar innehållade ordet antimicrobial.

  1. 21. Antibacterial materials for wound care applications utilizing antimicrobial peptides

    Författare :Edvin Blomstrand; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURVETENSKAP; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; NATURAL SCIENCES; ENGINEERING AND TECHNOLOGY; self-assembly; lyotropic liquid crystals; antibacterial surface; Antimicrobial peptides; Pluronic F-127; hydrogels;

    Sammanfattning : The spread of antibiotic resistance among bacteria has shown that the development of alternative treatments of infections is of vital importance. This thesis has looked at one potential candidate, antimicrobial peptides (AMPs), as an alternative or compliment to traditional antibiotics. LÄS MER

  3. 22. Relish and the Regulation of Antimicrobial Peptides in Drosophila melanogaster

    Författare :Marika Hedengren Olcott; Barbara Taylor; Jean-Marc Reichhart; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Drosophila immunity; NF-kappaB; Relish; antimicrobial peptides; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The fruit fly Drosophila melanogaster has been a powerful model system in which to study the immune response. When microorganisms breach the mechanical barrier of the insect, phagocytosing cells and a battery of induced antimicrobial molecules rapidly attack them. These antimicrobial peptides can reach micromolar concentrations within a few hours. LÄS MER

  4. 23. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    Författare :Miriam Geörg; Ann-Beth Jonsson; Ole E. Sørensen; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). LÄS MER

  5. 24. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

    Författare :Hava Lofton Tomenius; Dan I Andersson; Ørjan Samuelsen; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

    Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER

  7. 25. Antibacterial surface coatings for biomedical applications

    Författare :Saba Atefyekta; Chalmers University of Technology; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; MEDICIN OCH HÄLSOVETENSKAP; ENGINEERING AND TECHNOLOGY; MEDICAL AND HEALTH SCIENCES; Antimicrobial surfaces; mesoporous titania; elastin-like polypeptide; antimicrobial peptide; antibiotic delivery;

    Sammanfattning : Over the past decades there has been a significant increase in the diversity and function of biomaterials. Today, medical practices utilize a large number of biomaterials in the form of medical devices and implants. However, one major obstacle that limits the efficiency of biomaterials is their susceptibility to develop infection. LÄS MER