Visar resultat 21 - 25 av 385 avhandlingar innehållade ordet antimicrobial.
Sammanfattning : The spread of antibiotic resistance among bacteria has shown that the development of alternative treatments of infections is of vital importance. This thesis has looked at one potential candidate, antimicrobial peptides (AMPs), as an alternative or compliment to traditional antibiotics. LÄS MER
Sammanfattning : The fruit fly Drosophila melanogaster has been a powerful model system in which to study the immune response. When microorganisms breach the mechanical barrier of the insect, phagocytosing cells and a battery of induced antimicrobial molecules rapidly attack them. These antimicrobial peptides can reach micromolar concentrations within a few hours. LÄS MER
Sammanfattning : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). LÄS MER
Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER
Sammanfattning : Over the past decades there has been a significant increase in the diversity and function of biomaterials. Today, medical practices utilize a large number of biomaterials in the form of medical devices and implants. However, one major obstacle that limits the efficiency of biomaterials is their susceptibility to develop infection. LÄS MER