Sökning: "antigen"

Visar resultat 16 - 20 av 1373 avhandlingar innehållade ordet antigen.

  1. 16. Characterization of antibody specificity using peptide array technologies

    Författare :Björn Forsström; Mathias Uhlén; Markus Templin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody; Epitope mapping; Peptide array; Suspension bead array; Antigen; Specificity; Cross-reactivity; Immunization; Immunogenicity; Bioteknologi; Biotechnology;

    Sammanfattning : Antibodies play an important role in the natural immune response to invading pathogens. The strong and specific binding to their antigens also make them indispensable tools for research, diagnostics and therapy. LÄS MER

  2. 17. Computational analyses of biological sequences -applications to antibody-based proteomics and gene family characterization

    Författare :Mats Lindskog; Mathias Uhlén; Fredrik Sterky; Andersson Björn; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antigen; antibodies; antibody-based proteomics; biocomputing; bioinformatics; Bioinformatics; Bioinformatik;

    Sammanfattning : Following the completion of the human genome sequence, post-genomic efforts have shifted the focus towards the analysis of the encoded proteome. Several different systematic proteomics approaches have emerged, for instance, antibody-based proteomics initiatives, where antibodies are used to functionally explore the human proteome. LÄS MER

  3. 18. Mass Spectrometry and Affinity Based Methods for Analysis of Proteins and Proteomes

    Författare :Mårten Sundberg; Margareta Ramström; Jonas Bergquist; Christer Wingren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; proteomics; microarray; protein; antibody; antigen; affinity; validation; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : Proteomics is a fast growing field and there has been a tremendous increase of knowledge the last two decades. Mass spectrometry is the most used method for analysis of complex protein samples. It can be used both in large scale discovery studies as well as in targeted quantitative studies. LÄS MER

  4. 19. Protein microarrays for validation of affinity binders

    Författare :Mårten Sundberg; Peter Nilsson; Jochen Schwenk; Anders Isaksson; Afshin Ahmadian; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microarray; protein; antibody; antigen; affinity; validation;

    Sammanfattning : Is specificity an important issue regarding affinity reagents? What about the validation of affinity reagents today, is it good enough? This depends on the application and the producer of the reagent. Validation should be the most important marketing argument that can be found. LÄS MER

  5. 20. Immunoassays using high-Tc SQUIDs

    Författare :Fredrik Öisjöen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; YBCO; antigen.; magnetic nanoparticles; immunoassays; antibody; SQUID; High-Tc;

    Sammanfattning : The development of a system for immunoassays using highly sensitive high-Tc superconducting quantum interference devices (SQUIDs) and magnetic nanoparticles (MNPs) is described in this thesis.High-Tc SQUIDs were fabricated using pulsed laser deposition and photolithography. LÄS MER