Sökning: "antiepileptic drug"

Visar resultat 1 - 5 av 40 avhandlingar innehållade orden antiepileptic drug.

1. 1. Psychoactive prescription drug use disorders, misuse and abuse : Pharmacoepidemiological aspects

   Författare :Micaela Tjäderborn; Staffan Hägg; Johan Ahlner; Anna Jönsson; Morten Andersen; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychoactive prescription drugs; psychotropic drugs; prescription drug use disorders; prescription drug misuse; abuse; pharmacovigilance; drug utilization; pharmacoepidemiology;

   Sammanfattning : Background: There is a widespread and increasing use of psychoactive prescription drugs, such as opioid analgesics, anxiolytics, hypnotics and anti-epileptics, but their use is associated with a risk of drug use disorder, misuse and abuse. Today, these are globally recognized and emerging public health concerns. LÄS MER

3. 2. Generic Drug Switch in Epilepsy – Pharmacokinetic and Clinical Aspects

   Författare :Patrik Olsson; Helsingborg Kliniska Vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Generic drug; Antiepileptic drugs; Pharmacokinetics; Treatment outcome;

   Sammanfattning : Background and aim: Generic drugs contain the same active ingredients as brand- name drugs, with the advantage of much lower costs. The aim of this thesis was to contribute new knowledge to the ongoing debate on the safety of generic antiseizure drug (ASD) substitutions. There was a particular emphasis on the pharmacokinetic and clinical outcomes. LÄS MER

4. 3. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

   Författare :Faranak Azarbayjani; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

   Sammanfattning : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. LÄS MER

5. 4. Living with epilepsy : young people with uncomplicated epilepsy and adults with newly debuted epilepsy

   Författare :Lena Räty; Matti Sillanpää; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; antiepileptic drug; attitude; epilepsy; health; self-concept; self-esteem; seizure type; seizure control; sense of coherence; quality of life; MEDICINE; MEDICIN; Nursing Science;

   Sammanfattning : The aim of this thesis was to illuminate experiences of living with uncomplicated epilepsy, i.e. epilepsy without any associated neurological impainnents. The focus was on young people, aged 13- 22 (II, III, IV), and adults, aged 18-65 (I), with newly debuted epilepsy, i. LÄS MER

7. 5. Antiepileptic drug utilization : need of sex-specific information and decision support

   Författare :Linnéa Karlsson Lind; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Antiepileptic drugs are used for the treatment of epilepsy and for other neurological and psychiatric conditions, and therefore is prescribing of antiepileptic drugs a concern for physicians from many disciplines. The age and sex-specific prevalence, as well as the role of sex and gender aspects, vary between the conditions for which antiepileptic drugs are used. LÄS MER