Sökning: "anticoagulant"

Visar resultat 11 - 15 av 103 avhandlingar innehållade ordet anticoagulant.

  1. 11. Intracerebral hemorrhage and antithrombotic drugs - clinical aspects and prognostic outcomes

    Författare :Trine Apostolaki-Hansson; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracerebral hemorrhage; oral anticoagulant drug; reversal therapy; prognosis; survival; functional outcome; antithrombotic drugs;

    Sammanfattning : .... LÄS MER

  3. 12. The EGF-like Modules of Anticoagulant Protein S. Studies of Ca2+ binding and module interactions

    Författare :Yvonne Stenberg; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzymology; Proteins; Klinisk kemi; Clinical chemistry; calcium binding; Protein S; EGF-like module; Proteiner; enzymologi;

    Sammanfattning : Protein S functions as a cofactor to activated protein C (APC) in the degradation of factors Va and VIIIa. In plasma protein S circulates in two forms; 30-40 % circulates as free protein S molecules while the remaining 60-70 % exists in a 1:1 complex with C4b-binding protein (C4BP). Only the free form of protein S functions as a cofactor to APC. LÄS MER

  4. 13. Pro- and anticoagulant mechanisms in coronary artery disease. Clinical studies on factor VII and resistance to activated protein C

    Författare :Johan Holm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C; Factor VII; blood coagulation; myocardial infarction; APC resistance; Cardiovascular system; Kardiovaskulära systemet; warfarin;

    Sammanfattning : The triggering mechanism in myocardial infarction (MI) and unstable angina involves coronary thrombus formation following plaque rupture. Coagulation is initiated by tissue factor that activates factor VII (FVII), and is inhibited by protein C and its co-factor protein S. LÄS MER

  5. 14. The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9

    Författare :Mike Ufer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Drug metabolism; cytochrome P450; genetic polymorphism; genotyping; CYP2C9; phenprocoumon; warfarin; acenocoumarol; oral anticoagulants;

    Sammanfattning : Oral anticoagulants are widely used for the prevention of thromboembolic disorders. Warfarin (WA) is most commonly used world-wide, while phenprocoumon (PPC) is the first-line anticoagulant in some European countries including Germany. Each anticoagulant exists in two different enantiomeric forms and is administered orally as a racemate. LÄS MER

  7. 15. Essays on nonlinear time series analysis and health economics

    Författare :Anna Ovanfors; Handelshögskolan i Stockholm; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : .... LÄS MER