Sökning: "anticoagulant"
Visar resultat 1 - 5 av 103 avhandlingar innehållade ordet anticoagulant.
1. Pro- and anticoagulant activities of factor V
Sammanfattning : Coagulation factor V (FV) is activated by thrombin through proteolytic cleavage at Arg-709, Arg-1018 and Arg-1545. Upon thrombin activation, the active form of factor V (FVa) is formed. FVa functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin during coagulation. LÄS MER
2. Recurrent stroke : risk factors, predictors and prognosis
Sammanfattning : Background Many risk factors for stroke are well characterized and might, at least to some extent, be similar for first-ever stroke and for recurrent stroke events. However, previous studies have shown heterogeneous results on predictors and rates of stroke recurrence. LÄS MER
3. Anticoagulant protein C--structural and functional studies
Sammanfattning : Anticoagulant protein C is a vitamin K-dependent factor circulating in plasma as a zymogen of a serine protease. It is converted to its active form (APC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. APC inhibits the generation of thrombin by selective proteolytic inactivation procoagulant factors Va and VIIIa. LÄS MER
4. Anticoagulant and antiarrhythmic agents for atrial fibrillation
Sammanfattning : Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. AF treatment involves management of precipitating factors, rate- and rhythm control and anticoagulation for prevention of stroke and systemic thromboembolism. LÄS MER
5. Determinants of adverse events during oral anticoagulant treatment
Sammanfattning : Treament with oral anticoagulation is highly effective in reducing the burden of thromboembolic complications in several clinical conditions. The number of patients receiving oral anticoagulation is growing steadily. InSwedenabout 1.5 percent of the population receives treatment. LÄS MER