Sökning: "anti-platelet treatment"

Hittade 4 avhandlingar innehållade orden anti-platelet treatment.

  1. 1. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER

  3. 2. Improving outcomes in patients with coronary heart disease using national registers and platelet function testing

    Författare :Sasha Koul; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STEMI; NSTEMI; ACS; Ticagrelor; clopidogrel; prasugrel; treatment delays; bivalirudin; heparin; platelet function testing;

    Sammanfattning : Introduction: Ischemic heart disease is the leading cause of death worldwide. The aims of this thesis were to evaluate different contemporary approaches in coronary care with regard to mortality and myocardial infarction. LÄS MER

  4. 3. Platelet Inhibition and Bleeding in Coronary Artery Bypass Surgery

    Författare :Ulrica Alström; Elisabeth Ståhle; Ulf Schött; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bleeding; cardiac surgery; platelet inhibition; re-exploration; cost analysis; Anaesthetics and intensive care; Anestesiologi och intensivvård; Thoraxkirurgi; Thorax Surgery; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Sammanfattning : A substantial number of patients undergoing cardiac surgery are on dual anti-platelet treatment with clopidogrel and aspirin. A disadvantage with this treatment is increased risk of bleeding. Bleeding is a complication of major concern associated with adverse outcome for the patient and increased hospital resource utilization. LÄS MER

  5. 4. Platelet reactivity and comorbidities in acute coronary syndrome

    Författare :Fredrik Björklund; Thomas Mooe; David Erlinge; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute coronary syndrome; myocardial infarction; platelet reactivity; platelet aggregation; Inflammation; infection; diabetes mellitus; chronic kidney disease; acute kidney injury; Cardiology; kardiologi;

    Sammanfattning : Background In the event of an acute coronary syndrome (ACS), the risk of death and complications such as stroke and re-infarction is high during the first month. Diabetes, impaired kidney function, elevated markers of systemic inflammation and high level of platelet reactivity have all been associated with worsened prognosis in ACS patients. LÄS MER