Sökning: "anti-parasitic"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet anti-parasitic.

  1. 1. Anti-parasitic and anti-viral immune responses in insects

    Författare :Olle Terenius; Ingrid Faye; Kenneth Söderhäll; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolin; Hyalophora cecropia; Antheraea pernyi; Drosophila melanogaster; anti-viral; anti-parasitic; rna interference; microarray; innate immunity; Genetics; Genetik;

    Sammanfattning : Insects encounter many microorganisms in nature and to survive they have developed counter measures against the invading pathogens. In Drosophila melanogaster research on insect immunity has mainly been focused on infections by bacteria and fungi. LÄS MER

  2. 2. Drug Repositioning for Cancer Treatment : Novel Candidate Identification Strategies

    Författare :Madiha Nazir; Mårten Fryknäs; Sigurd Vitols; Uppsala universitet; []
    Nyckelord :cancer treatment; drug repositioning; Phosphodiesterase 3A PDE3A ; apoptosis; combination screening;

    Sammanfattning : Regardless of the enormous investments in cancer research and drug development, the proportion of approved drugs in oncology is low compared to other indications, and new avenues are needed. One attractive approach in this regard is drug repositioning where new uses outside the scope of the original medical indications for existing drugs are identified. LÄS MER

  3. 3. Elucidating the Gating Mechanism of Cys-Loop Receptors

    Författare :Özge Yoluk; Erik Lindahl; Philip Biggin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ion channel; gating; simulation; molecular dynamics; receptor; cys-loop; modelling; Teoretisk kemi och biologi; Theoretical Chemistry and Biology; Biological Physics; Biologisk fysik;

    Sammanfattning : Cys-loop receptors are membrane proteins that are key players for the fast synaptic neurotransmission. Their ion transport initiates new nerve signals after activation by small agonist molecules, but this function is also highly sensitive to allosteric modulation by a number of compounds such as anesthetics, alcohol or anti-parasitic agents. LÄS MER

  4. 4. Studies of different secondary metabolites : Natural products from the mevalonate pathway

    Författare :Mariela Alejandra Gonzales Ramirez; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Natural products; fungi; Galiellalactone; Galiella rufa; Trichilia adolfi; benzofuran;

    Sammanfattning : Natural products, also called secondary metabolites, are small molecules that are not involved in main life processes. These can be produced by any living organism and play important roles as chemical weapons, protecting the organism from the competitive environment. LÄS MER

  5. 5. Signaling pathways in the activation and proliferation of Drosophila melanogaster blood cells

    Författare :Carl-Johan Zettervall; Marie Meister; Umeå universitet; []
    Nyckelord :innate immunity; cellular immunity; molecular signaling; molekylärbiologi; Molecular Biology;

    Sammanfattning : The larva of the fruit fly Drosophila melanogaster is an excellent model to study the molecular control of innate cellular immune responses. Cellular responses take place, and can be studied, following infestation of the wasp Leptopilina boulardi. This response includes proliferation and activation (differentiation) of the blood cells (hemocytes). LÄS MER