Sökning: "anti-GBM nephritis"

Hittade 1 avhandling innehållade orden anti-GBM nephritis.

  1. 1. Molecular dissection of the Goodpasture epitope

    Författare :Thomas Hellmark; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; autoimmune; anti-GBM nephritis; glomerulonephritis; nephrology; Urology; nefrologi;

    Sammanfattning : Goodpasture disease is a prototype autoimmune disease that is characterized by a rapidly progressive glomerulonephritis, with or without lung haemorrhage, associated with autoantibodies against the glomerular basement membrane. The major antigen has previously been shown to be the non-collagenous domain of the a3 chain of type IV collagen, one of the six known a chains of type IV collagen. LÄS MER