Sökning: "anti-CCP"

Visar resultat 11 - 15 av 16 avhandlingar innehållade ordet anti-CCP.

  1. 11. Aspects of the role of mineral oil as immunological adjuvants in rheumatoid arthritis

    Författare :Berit Sverdrup; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rheumatoid arthritis; adjuvant; mineral oil; experimental; DA rat; epidemiologic; cohort; case-control.;

    Sammanfattning : Environmental factors are likely contributing factors in the development of Rheumatoid Arthritis (RA), an autoimmune disease, for which etiologic factors are still poorly known. Mineral oils are efficient adjuvants which increase immunological responses and are used in animal immunization and for induction of different experimental autoimmune diseases including arthritis. LÄS MER

  3. 12. Functional Role of Immune Complexes in Rheumatic and Parasitic Diseases

    Författare :Erik Åhlin; Johan Rönnelid; Karlis Pauksens; Bo Nilsson; Joachim Lundahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical immunology; Klinisk immunologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Immune complexes (IC) have key pathological roles in both autoimmune and infectious diseases. In this thesis functional mechanisms behind IC-driven inflammation in rheumatic diseases and tropical infections have been studied, with special focus on the contribution of autoantibodies and cytokine-inducing properties of IC. LÄS MER

  4. 13. The Immunopathology of Rheumatoid Arthritis and Leishmania donovani Infection in Sudan

    Författare :Amir I. Elshafie; Johan Rönnelid; Anders Bengtsson; Uppsala universitet; []
    Nyckelord :Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Immune complexes (IC) and antibody production against self-antigens play a pathological key role in the development of autoimmunity that occurs in patients with parasitic infections and rheumatic diseases. My studies have targeted two groups of patients from Sudan; patients with visceral leishmaniasis (VL) and patients with rheumatoid arthritis (RA). LÄS MER

  5. 14. Ultrasound and fluorescence optical imaging biomarkers for early diagnosis and prediction of rheumatoid arthritis

    Författare :Yogan Kisten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prevention of rheumatoid arthritis (RA) is most desirable together with curative treatment which is, however, not yet available. Today, the correct timely diagnosis and early treatment interventions to prevent disease progression remain the best options for our patients. LÄS MER

  7. 15. Arthritogenic and immunogenic properties of modified autoantigens

    Författare :Karin Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Post-translational modifications; pH; chlorination; citrullination; CII; CIA; RA;

    Sammanfattning : Rheumatoid arthritis is a chronic inflammatory joint disorder with autoimmune features in which both genetic and environmental factors are potential contributors to the arthritogenic process. In this thesis work we aimed to increase the understanding of early pathogenic events underlying the development of this complex disease by investigating the arthritogenic and immunogenic properties of modified autoantigens in experimental settings as well as in RA patients. LÄS MER