Sökning: "animal model"

Visar resultat 6 - 10 av 1019 avhandlingar innehållade orden animal model.

1. 6. Ontogeny and Population Biology of a Sex-Limited Colour Polymorphism

   Författare :Jessica Abbott; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; embryologi; ontogeni; animal morphology; embryology; Utvecklingsbiologi; Damselflies; Colour polymorphism; Development; Frequency-dependence; Morphology; growth animal ; ontogeny; Animal anatomy; Development biology; Djurs anatomi och morfologi; Population divergence; Animal ecology; Djurekologi;

   Sammanfattning : This study has involved investigation of number of populations of the damselfly Ischnura elegans over several years, looking at frequency changes over time, morphological differences between the sexes and the morphs, differences in growth rate and development time, differences in fecundity between the morphs, and genetic differentiation between populations. I. LÄS MER

3. 7. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model

   Författare :Åsa Melhus; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; conjugate vaccine; protection; virulence; acute otitis media; Haemophilus influenzae; animal model; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. LÄS MER

4. 8. Genetic Studies of Rheumatoid Arthritis using Animal Models

   Författare :Niklas Nordquist; William Dietrich; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. LÄS MER

5. 9. Unraveling the genetics of lymphocytic thyroiditis using the dog as a model

   Författare :Katarina Sundberg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : The domestic dog, with its unique genetic structure formed by domestication and recent breed creation, has been proven to be an excellent model for mapping disease genes. In this thesis, we use the dog as a model to investigate the prevalence and genetic background of canine lymphocytic thyroiditis (CLT), one of the most common immune related diseases in dogs. LÄS MER

7. 10. Beta Cell Function: from Human Genetics to Animal Models

   Författare :Martins Kalis; Diabetes - immunovirologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; animal model; Dicer1; genetics; genetic association; single nucleotide polymorphism; SNP; INS-1E; AAT; FOXP3; beta cell function; insulin secretion; FFAR1; insulin; T2D; glucose; T1D;

   Sammanfattning : Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. LÄS MER