Sökning: "angiotensin"

Visar resultat 6 - 10 av 193 avhandlingar innehållade ordet angiotensin.

  1. 6. Design and synthesis of -turn peptidomimetics : Applications to angiotensin II

    Författare :Susanna Lindman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; peptide synthesis; turn mimetics; molecular modelling; receptor binding affinity; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Sammanfattning : This study addresses the issue of how to convert peptides into drug-like non-peptides while retaining the biological activity at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. Small bioactive peptides are in most cases conformationally flexible molecules. LÄS MER

  3. 7. Angiotensin II receptors in the small intestine. Expression analyses and functional considerations

    Författare :Emma Spak; Göteborgs universitet; []
    Nyckelord :renin-angiotensin system; angiotensin II; AT1; AT2; small intestine; jejunum; hypovolemia; small bowel transplantation; smooth muscle; contractility;

    Sammanfattning : .... LÄS MER

  4. 8. Impact of the upper gut on body fluid regulation and blood pressure in man - potential involvement of a locally expressed renin-angiotensin system

    Författare :Peter Hallersund; Göteborgs universitet; []
    Nyckelord :angiotensin; stomach; duodenum; sodium; salt; diuresis; appetite; gastric bypass; blood pressure;

    Sammanfattning : This thesis explores the role of the upper gut in the regulation of diuresis and blood pressure control in relation to the novel finding of a mucosa-located renin-angiotensin system (RAS). RAS is a regulatory super-system vital for body fluid homeostasis and blood pressure control. LÄS MER

  5. 9. Vascular receptor changes in ischemic stroke

    Författare :Emelie Stenman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

  7. 10. Pharmacological interactions between angiotensin-converting enzyme (ACE) inhibitors, bradykinin and nitric oxide

    Författare :Karin Persson; Karl-Erik Andersson; Linköpings universitet; []
    Nyckelord :angiotensin-converting enzyme; angiotensin-converting enzyme inhibitors; atherosclerosis; bradykinin; endothelium; in vitro; nitric oxide; MEDICINE; MEDICIN;

    Sammanfattning : Cardiovascular diseases are a major cause of death in Western countries. Angiotensin-converting enzyme (ACE) is as a key enzyme in the renin-angiotensin system involved in the regulation of blood pressure, and water and electrolyte balance in the body. LÄS MER