Sökning: "angiotensin receptor blocker"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden angiotensin receptor blocker.
1. Vascular receptor changes in ischemic stroke
Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER
2. Mortality in Oxygen-Dependent Chronic Obstructive Pulmonary Disease and Possibilities for Pharmacological Interventions
Sammanfattning : Background Chronic obstructive pulmonary disease (COPD) is a major and rising cause of mortality worldwide, especially in women. Patients with chronic hypoxia owing to COPD are treated with long-term oxygen therapy (LTOT) but have high morbidity and mortality. LÄS MER
3. Effects of the angiotensin II type 1 receptor blocker (AT₁ receptor blocker) candesartan cilexetil on systemic and renal haemodynamics in hypertensive patients
Sammanfattning : Established primary hypertension is primarily characterised by elevated peripheral resistance and an increase in renal vascular resistance. Antagonism of angiotensin II may be a particularly relevant intervention in this condition, as angiotensin II is known to act both as a powerful vasoconstrictor and as a stimulus to vascular hyperthrophy. LÄS MER
4. Mesentric hemodynamics and effects of angiotensin II during circulatory stress
Sammanfattning : Mesenteric hypoperfusion and ischemia is considered to be deleterious to the intestinal mucosal barrier function and it is suggested that the renin-angiotensin system plays a pivotal role in the regulation of mesenteric perfusion.The present thesis examines the effects of the specific AT1 receptor blocker candesartan on mesenteric hemodynamics during acute hypovolemia and endotoxinemia. LÄS MER
5. The Role of Angiotensin II in Experimental Acute Kidney Injury and Cardiorenal Failure
Sammanfattning : Blood pressure and fluid regulation are kept constant through the interaction between heart and kidneys. When the systemic blood pressure decreases, the levels of the hormone Angiotensin II increase, leading to vasoconstriction and therefore increased blood pressure. LÄS MER