Sökning: "androgen"

Visar resultat 6 - 10 av 216 avhandlingar innehållade ordet androgen.

  1. 6. Mechanisms behind growth of castration-resistant prostate cancer bone metastases

    Författare :Emma Jernberg; Pernilla Wikström; Jack Schalken; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; castration-resistance; bone metastases; androgen receptor; intratumoral steroidogenesis; androgen receptor splice variants; androgen receptor amplification; patologi; Pathology;

    Sammanfattning : Background: The first-line treatment for patients with advanced prostate cancer (PC) is androgen deprivation therapy. This therapy is initially effective, but after some time tumors relapse, predominantly within the bone, and are then termed castration-resistant prostate cancer (CRPC). LÄS MER

  3. 7. Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1

    Författare :Helene Gustavsson; Göteborgs universitet; []
    Nyckelord :Prostate cancer; Androgen-independent; Castration resistant; Hormone refractory; Angiogenesis; Microvessel density; ADAMTS1; LNCaP; VEGF; TSP1;

    Sammanfattning : Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a highly aggressive and androgen-independent (AI) manner. LÄS MER

  4. 8. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses

    Författare :Kristina Lundin; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Functional domain; Genetic predisposition; Reproductive function; Sex hormone; Transactivation function; Repeat; Polymorphism; Androgen receptor; Transcription factor; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. LÄS MER

  5. 9. Modulation of androgen receptor function by brominated flame retardants

    Författare :Joubert Banjop Kharlyngdoh; Per-Erik Olsson; Peter Pärt; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DBE-DBCH; TBP-AE; TBP-BAE; TBP-DBPE; androgen receptor; endocrine disrupters; brominated flame retardant; Biology; Biologi;

    Sammanfattning : .... LÄS MER

  7. 10. Influences of Endogenous and Exogenous Hormones in Middle-aged Women

    Författare :Ali Khatibi Esfanjani; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipid profile; Blood pressure; Non-hormonal drug; Middle-aged women; Cardiovascular disease; Menopause; Androstendione; Androgen; Testosterone;

    Sammanfattning : Endogenous and exogenous sex hormones are of pivotal importance for women’s health. Hormone therapy has been widely studied but there is limited data about androgen and androgen replacement therapy. LÄS MER