Sökning: "androgen"

Visar resultat 21 - 25 av 216 avhandlingar innehållade ordet androgen.

  1. 21. Genetics of androgen disposition : implications for doping tests

    Författare :Jenny Jakobsson Schulze; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Anabolic androgenic steroids (AAS) are derivatives of testosterone. Doping with AAS is a severe challenge to the vision, moral and ethics in sports and has also become an increasing problem in society. Testosterone abuse is conventionally assessed by the urinary testosterone glucuronide/ epitestosterone glucuronide (T/E) ratio, levels above 4. LÄS MER

  3. 22. The role of androgen in prostate cancer cell invasion

    Författare :Yin-Choy Chuan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer (PCa) is the most commonly diagnosed cancer in men in developed countries. Androgen deprivation therapy (ADT) is the mainstay treatment for patient diagnosed with PCa. However, the cancer will eventually relapse with metastatic cancer and become resistant to the treatment. LÄS MER

  4. 23. Sex steroids and social behavior: from mouse to human

    Författare :Sara Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; social memory; sociability; androgen receptor; sex steroids; genetic variations;

    Sammanfattning : Social behavior is a classification of various behaviors such as sexual behavior, aggressive behavior, social memory and sociability. These behaviors are under the regulation of the brain, and the sex steroids influence important brain regions that control these behaviors in both humans and other animals. LÄS MER

  5. 24. Invasive and Metastatic Properties of Advanced Prostate Cancer

    Författare :Karin Jennbacken; Göteborgs universitet; []
    Nyckelord :Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

    Sammanfattning : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. LÄS MER

  7. 25. A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

    Författare :Zandra Hagman; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; prostate cancer; androgen receptor; MET; HGF; miR-34c; miR-205; AGO2-RIP-Chip; noncoding RNA;

    Sammanfattning : The complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. LÄS MER