Sökning: "androgen activity"

Visar resultat 21 - 25 av 59 avhandlingar innehållade orden androgen activity.

1. 21. Structure, evolution and expression of glandular kallikrein genes

   Författare :Yvonne Ceder; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

   Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER

3. 22. Improving alternatives assessment of plastic additives : exploring in silico tools to identify less hazardous flame retardants

   Författare :Ziye Zheng; Patrik L. Andersson; Hans Peter Arp; Gregory Peters; Gerrit Schüürmann; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Chemical alternatives assessment; plastic additives; flame retardants; hazard; emission; in silico; modeling; quantitative structure-activity relationship QSAR ; multi-criteria decision analysis MCDA ; environmental science; miljövetenskap; organisk kemi; Organic Chemistry; ekotoxikologi; Ecotoxicology; Toxicology; toxikologi;

   Sammanfattning : Alternatives assessment is applied for replacing hazardous chemicals with viable, safer substitutes. High quality experimental hazard data, however, are usually unavailable for this purpose, and obtaining in silico data is the only approach to fill in data gaps. LÄS MER

4. 23. Testosterone treatment in women : aspects on sexuality, well-being and metabolism

   Författare :Angelique Flöter Rådestad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Androgens; testosterone; testosterone undecanoate; sexuality; well-being; oophorectomy; lipids; lipoproteins; bone markers; body composition; female androgen insufficiency;

   Sammanfattning : The expected postmenopausal lifetime of women in the western world is about 30 years. Hormones, such as estrogen and progestogen, may affect the quality of postmenopausal life and have been well studied. LÄS MER

5. 24. Hormonal and paracrine influences on Leydig cell steroidogenesis

   Författare :Nina Renlund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Androgen production by Leydig cells is critical for development of the male reproductive organs and for maintaining normal body homeostasis and fertility later in life. Biosynthesis of testosterone is driven by secretion of the gonadotropin, luteinizing hormone (LH) from the pituitary. LÄS MER

7. 25. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

   Författare :Jens Ceder; Malmö (Abrahamsson) Urologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

   Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER