Sökning: "anders hallberg"

Visar resultat 21 - 25 av 31 avhandlingar innehållade orden anders hallberg.

  1. 21. Design and Synthesis of Malarial Aspartic Protease Inhibitors

    Författare :Karolina Ersmark; Anders Hallberg; Michael Rowley; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; malaria; plasmepsin; aspartic protease; protease inhibitor; macrocycle; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Malaria is one of the major public health problems in the world. Approximately 500 million people are afflicted and almost 3 million people die from the disease each year. Of the four causative species Plasmodium falciparum is the most lethal. LÄS MER

  3. 22. Design and Synthesis of Novel AT2 Receptor Ligands : From Peptides to Drug-Like Molecules

    Författare :Jennie Georgsson; Anders Hallberg; Kevin Burgess; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; angiotensin II; AT1; AT2; AT2 receptor agonist; peptidomimetics; γ-turn mimetics; carbonylation; microwave; molybdenum hexacarbonyl; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Many peptide receptors are of pharmaceutical interest and there is thus a need for new ligands for such receptors. Unfortunately, peptides are not suitable as orally administrated drugs since they are associated with poor absorption, rapid metabolism and low sub-receptor selectivity. LÄS MER

  4. 23. Intraocular pressure : clinical aspects and new measurement methods

    Författare :Gauti Jóhannesson; Christina Lindén; Per Hallberg; Anders Eklund; Boel Bengtsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intraocular pressure; glaucoma; tonometry; ISO; LASEK; CCT; curvature; Ophtalmiatrics; Oftalmiatrik; Ophtalmology; oftalmiatrik;

    Sammanfattning : Intraocular pressure (IOP) measurement is a routine procedure and a fundament in glaucoma care. Elevated IOP is the main risk factor for glaucoma, and to date, reduction of IOP is the only possible treatment. In a retrospective clinical material, the prevalence of open angle glaucoma was estimated on the west coast of Iceland. LÄS MER

  5. 24. CNS Targets for GH and IGF-1 : Emphasis on Their Regulation in Relation to Cognitive Processes

    Författare :Madeleine Le Grevès; Fred Nyberg; Anders Hallberg; Sigbritt Werner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; Central nervous system; Growth hormone; Insulin-like growth factor-1; Receptor mRNA regulation; N-methyl-D-aspartate receptor mRNA; Morris water maze; Farmaceutisk farmakologi; Pharmaceutical pharmacology; Farmaceutisk farmakologi;

    Sammanfattning : The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the central nervous system (CNS) has grown during the past decade. GH has been associated with psychological functions as sleep, mood, general well-being and learning and memory. LÄS MER

  7. 25. Selectivity in Palladium- and Enzyme-Catalyzed Reactions : Focusing on Enhancement of Reactivity

    Författare :Peter Nilsson; Anders Hallberg; Mats Larhed; Matthias Beller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Palladium; Heck; PCR; Microwaves; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Catalysis has a profound impact on all living species on the earth. Nature’s catalysts, the enzymes, have the ability to selectively promote a specific bio-chemical transformation, given the required substrate. LÄS MER