Sökning: "ancient genomics"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden ancient genomics.

  1. 1. Ancient genomics of Baltic seals : Insights on the past Baltic grey seal and harp seal populations

    Författare :Maiken Hemme Bro-Jørgensen; Kerstin Lidén; Morten Tange Olsen; Aikaterini Glykou; Olle Karlsson; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Ancient DNA; Baltic Sea; DNA preservation; extinction; mitogenome; seal hunting; sex identification; arkeologi med inriktning mot laborativ arkeologi; Scientific Archaeology;

    Sammanfattning : This thesis aims to study and describe the ancient populations of grey and harp seals in the Baltic Sea, and to present new methodological approaches for general use in ancient DNA studies.The dissertation is comprised of five studies: a review of the use of paleogenetics in studying ancient human-marine mammal interactions; a method paper investigating patterns of DNA preservation in ancient pinniped samples; a method paper presenting a genetic sex identification method for ancient pinnipeds; a population genomic study of the Baltic grey seal; and a population genomic study of the now extinct Baltic harp seal. LÄS MER

  3. 2. Methodology and Infrastructure for Statistical Computing in Genomics : Applications for Ancient DNA

    Författare :Kristiina Ausmees; Carl Nettelblad; Mattias Jakobsson; Flora Jay; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical computing; genotype imputation; ancient DNA; deep learning; dimensionality reduction; genetic clustering; distributed computing; Scientific Computing; Beräkningsvetenskap;

    Sammanfattning : This thesis concerns the development and evaluation of computational methods for analysis of genetic data. A particular focus is on ancient DNA recovered from archaeological finds, the analysis of which has contributed to novel insights into human evolutionary and demographic history, while also introducing new challenges and the demand for specialized methods. LÄS MER

  4. 3. Genomic analysis of the process leading up to the extinction of the woolly mammoth

    Författare :Patrícia Pečnerová; Love Dalén; Mark Thomas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; woolly mammoth; Mammuthus primigenius; extinction; Wrangel Island; ancient DNA; palaeogenetics; population genetics; genomics; genomic erosion; genetic drift; inbreeding; population size; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Sammanfattning : Species worldwide are subject to contractions in both abundance and geographical range, and their persistence in a changing environment may thus depend on the ability to survive in small and fragmented populations. Despite the urgent need to understand how extinction works, our knowledge of pre-extinction genetic processes is limited because techniques allowing population and conservation genomics to be studied in wild threatened populations have become available only recently. LÄS MER

  5. 4. Survivors of the Sea: Investigating the genomics and survival strategies of the diatom Skeletonema marinoi

    Författare :Matthew I. M. Pinder; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diatoms; Skeletonema marinoi; Resting stages; Bioinformatics; Genomics; Gene expression; Metabarcoding;

    Sammanfattning : Diatoms are an ecologically important group of phytoplankton, responsible for around 20% of global primary production. One of the features contributing to their success is their ability to form resting stages, a response to adverse conditions in which they enter a dormant state and sink to the sediment. LÄS MER

  7. 5. People of the Dolmens and Stone Cists : An archaeogenetic Investigation of Megalithic Graves from the Neolithic Period on Gotland

    Författare :Magdalena Fraser; Kjel Knutsson; Mattias Jakobsson; Paul Wallin; Anders Götherström; Per Åke Persson; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; archaeology; aDNA; ancient genomics; archaeogenetics; mtDNA; osteology; radiocarbon dating; Strontium; Carbon; Nitrogen; TRB; PWC; BAC; CWC; dolmen; stone cist; population demography; diet; mobility; cultural duality; admixture; kinship; Neolithic period; Early Bronze Age; Europe; Baltic Sea area; Scandinavia; Gotland; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The study of ancient genomics of pre-historic human remains has in recent years offered unprecedented knowledge regarding pre-historic migration and population structure on the European continent which has fundamentally altered the current views in the archaeological community. However, the merging of the two fields, archaeology and genetics, is still in its infancy and much work is still needed in order for these fields to integrate. LÄS MER