Sökning: "anandamide"
Visar resultat 6 - 10 av 14 avhandlingar innehållade ordet anandamide.
6. Microvascular inflammatory response in the skin
Sammanfattning : This thesis examines the microvascular inflammatory response in the skin. The microvascular response includes vasodilatation and plasma exudation. In the first three studies, the combined response was measured in guinea pig skin with a technique based on detection of radiolabelled protein. LÄS MER
7. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?
Sammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER
8. Endocannabinoid metabolism : the impact of inflammatory factors and pharmacological inhibitors
Sammanfattning : The endocannabinoid (eCB) system is an endogenous signaling system consisting of ligands (referred to as endocannabinoids, eCBs), receptors and metabolic enzymes. The eCB system is involved in homeostatic control of a variety of biological functions such as neuronal signaling, mood, appetite and pathological conditions such as pain, inflammation and tumour progression. LÄS MER
9. Mantle cell lymphoma : studies of predictive markers, the role of the microenvironment in disease development and identification of new potential targets for therapy
Sammanfattning : Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma and accounts for 5-10 % of all non-Hodgkin lymphomas (NHL). In Sweden, the incidence of NHL is 21.6 and 15.3 per 100 000 persons for men and women, respectively, which result in almost 100-200 new MCL cases per year. LÄS MER
10. The endocannabinoid system : a translational study from Achilles tendinosis to cyclooxygenase
Sammanfattning : The endogenous cannabinoids anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert their effect by activating cannabinoid receptors (CB). These receptors mediate a broad range of physiological functions such as beneficial effects in pain and inflammation, although little is known about the expression of CB receptors in human pain conditions. LÄS MER