Sökning: "amyloid"
Visar resultat 21 - 25 av 499 avhandlingar innehållade ordet amyloid.
21. Evaluation of amyloid precursor protein and ß-amyloid as biomarkers for Alzheimer s disease
Sammanfattning : Alzheimer s disease (AD) is a neurodegenerative disorder characterised by accumulations of neurofibrillary tangles and amyloid plaques. The major components of the amyloid deposits are the ß-amyloid (Aß) peptides derived from the amyloid precursor protein (APP). LÄS MER
22. Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia
Sammanfattning : Heparan sulfate (HS) is a highly sulfated polysaccharide expressed on the cell surface and in the extracellular matrix, interacting with a large number of proteins. HS is implicated in human diseases, including different types of cancer and amyloid diseases such as Alzheimer's disease (AD). LÄS MER
23. Cellular Uptake of Amyloid Forming Proteins Related to Neurodegenerative Disease
Sammanfattning : Aggregation and deposition of disease-associated protein is a pathological hallmark of several human disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). These diseases are characterized by the formation of amyloid-β (Aβ) and α-synuclein (α-syn) amyloid fibrils, in extracellular and intracellular locations, respectively. LÄS MER
24. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides
Sammanfattning : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. LÄS MER
25. The Impact of Amyloid Peptides on Pericytes in Alzheimer's Disease
Sammanfattning : .... LÄS MER