Sökning: "amino"

Visar resultat 6 - 10 av 1703 avhandlingar innehållade ordet amino.

1. 6. Conformations of amino acids characterized by theoretical spectroscopy

   Författare :Hongbao Li; Yi Luo; Tanja van Mourik; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amino acids; spectroscopy; Teoretisk kemi och biologi; Theoretical Chemistry and Biology;

   Sammanfattning : Amino acids are the basic building blocks of proteins. The determinationof their structures plays an important role in correctly describing the functionsof the proteins. LÄS MER

3. 7. The Biological Importance of the Amino Acid Transporter SLC38A10 : Characterization of a Knockout Mouse

   Författare :Frida A. Lindberg; Robert Fredriksson; Erika Roman; Karin Nordenankar; Vootele Vöikar; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute carrier; SLC; SNAT10; SLC38A10; phenotyping; behavior; amino acids; knockout mouse model; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : The biggest group of transporters, the solute carriers (SLCs), has more than 400 members, and about 30% of these are still orphan. In order to decipher their biological function and possible role in disease, there is a need for characterization of these. LÄS MER

4. 8. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods

   Författare :Javier Zurita; Leopold Ilag; Ulrika Nilsson; Margareta Törnqvist; Natalia Tretyakova; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amino acids; LC MS; fixed-charge derivatization; BMAA; chiral separation; pheromones; arctic aerosols; serum albumin adducts; benzo[a]pyrene diol epoxides; high-resolution MS; Analytical Chemistry; analytisk kemi;

   Sammanfattning : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). LÄS MER

5. 9. Selective transfer hydrogenations : Catalyst development and mechanistic investigations

   Författare :Jenny Wettergren; Hans Adolfsson; Serafino Gladiali; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric catalysis; transfer hydrogenation; transition metal; amino acids; amino alcohols; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

   Sammanfattning : By generating a library of amino acid-based ligands, pseudo-dipeptides, and combining them with transition metals, we have created selective and efficient ruthenium and rhodium catalysts for the asymmetric transfer hydrogenation of ketones. The ruthenium-catalyzed reaction was studied in detail, and we found that alkali metals play a crucial role for the reactivity and selectivity of the reaction. LÄS MER

7. 10. Asymmetric Synthesis of C-Glycosylated Amino Acids : Incorporation in Collagen Glycopeptides and Evaluation in a Model for Rheumatoid Arthritis

   Författare :Tomas Gustafsson; Jan Kihlberg; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Total synthesis; stereoselective synthesis; chiral glycine templates; Evan’s alkylation; asymmetric hydrogenation; alpha-amino acid synthesis; C-glycoside; rheumatoid arthritis; MHC; T cell; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis describes stereoselective syntheses of four amino acids, three of which are C-glycosidic analogues of glycosylated amino acids. The overall goal of the project was to probe the interactions between MHC molecules, glycopeptide antigens and T cell receptors, that are essential for development of collagen induced arthritis. LÄS MER