Sökning: "alveolar immune response"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden alveolar immune response.

  1. 16. Genetic factors influencing susceptibility to intracellular infections

    Författare :Fabio Sánchez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Genetic susceptibility; leprosy; leishmaniasis; HIV; quantitative trait locus; linkage analysis; multigenic; severity.;

    Sammanfattning : Genetics of susceptibility to infection is a complex trait in which many factors from the host, the parasite and the environment, interact to produce different clinical manifestations of disease. This thesis explores the relationship between the first infectious susceptibility gene ever cloned, SLC11A1 and the occurrence of intracellular infections (leprosy, leishmaniasis and HIV infection) in several populations of humans. LÄS MER

  3. 17. Sarcoidosis : expression of cell regulatory markers and the influence of patient phenotype on bronchoalveolar lavage cell differential counts

    Författare :Muntasir Abo Al Hayja; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sarcoidosis is a systemic inflammatory disease that can affect almost any organ, but the respiratory system is affected in more than 90% of the cases. To elicit an immune response, an antigen(s) is processed by antigen-presenting cells (APCs), e.g. LÄS MER

  4. 18. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

    Författare :P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

    Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER

  5. 19. Aspects of inflammation in chronic obstructive pulmonary disease : a clinical study

    Författare :Magnus J Löfdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chronic pbstructive pulmonary disease; bronchoscopy; bronchoalveolar lavage; inflammation; flow cytometry; bronchial biopsies;

    Sammanfattning : Development of chronic obstructive pulmonary disease (COPD) involves an amplified inflammatory response to tobacco smoke that results in a limitation of airflow. At present, the mechanisms underlying these inflammatory processes are not fully understood and insight into these mechanisms could be obtained through comparison of the processes in patients with COPD and appropriate controls. LÄS MER

  7. 20. Investigation of nanoparticle-cell interactions for development of next generation of biocompatible MRI contrast agents

    Författare :Natalia Abrikossova; Kajsa Uvdal; Caroline Brommesson; Eva Särndahl; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Progress in synthesis technologies and advances in fundamental understanding of materials with low dimensionality has led to the birth of a new scientific field, nanoscience, and to strong expectations of multiple applications of nanomaterials. The physical properties of small particles are unique, bridging the gap between atoms and molecules, on one side, and bulk materials on the other side. LÄS MER