Sökning: "alpha"

Visar resultat 6 - 10 av 1299 avhandlingar innehållade ordet alpha.

  1. 6. Biofeedback of EEG alpha : methodological aspects and theoretical considerations

    Författare :Sarah S. Knox; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psykofysik;

    Sammanfattning : .... LÄS MER

  3. 7. Pathophysiological effects of alpha-synuclein on SNARE complex proteins in models of alpha-synucleinopathies

    Författare :Emma Brolin; Joakim Bergström; Anna Erlandsson; Martin Ingelsson; Arianna Bellucci; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha-synuclein; Parkinson’s disease; synaptosome; SNARE complex; proximity ligation assay; extracellular vesicles;

    Sammanfattning : Accumulation and spread of alpha-synuclein (α-syn) aggregates are central to the disease pathogenesis of Parkinson’s disease and dementia with Lewy bodies, collectively known as α-synucleinopathies. Native α-syn is a monomeric presynaptic protein that can act as a molecular chaperone for the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex assembly. LÄS MER

  4. 8. GDNF and alpha-synuclein in nigrostriatal degeneration

    Författare :Maria Chermenina; Ingrid Strömberg; Guido Nikkhah; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; GDNF; ventral mesencephalon; lateral ganglionic eminence; alpha-synuclein; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Sammanfattning : Parkinson’s disease is a common neurological disorder with a complex etiology. The disease is characterized by a progressive loss of dopaminergic cells in the substantia nigra, which leads to motor function and sometimes cognitive function disabilities. LÄS MER

  5. 9. Pathogenic effects of alpha-synuclein: modifications and toxicity

    Författare :Natalie Landeck; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Nyckelord :Parkinson s disease; adeno-associated viral vector; animal models; alpha-synuclein; substantia nigra; dopaminergic neurons; phosphorylation; aggregation; toxicity;

    Sammanfattning : Accumulation of intraneuronal inclusions, containing mainly a protein called alpha-synuclein (asyn), is thought to play a critical role in neurodegenerative disorders such as Parkinson's disease (PD). In these so called Lewy bodies, the majority of asyn is phosphorylated at serine 129 (pS129) suggesting that post-translational modifications may play a critical role in the process of aggregate formation. LÄS MER

  7. 10. Alpha-synuclein: pathology, peripheral expression, and environmental interactions

    Författare :Caroline Haikal; Neural plasticitet och reparation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease PD ; alpha-synuclein; Bacterial amyloids; Synucleinopathies; Gastrointestinal GI tract; DMSO;

    Sammanfattning : .... LÄS MER