Sökning: "alpha-lactalbumin"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet alpha-lactalbumin.

  1. 1. Nuclear mechanisms in cell death induced by HAMLET (human alpha-lactalbumin made lethal to tumour cells)

    Detta är en avhandling från Caroline Düringer, Sölvegatan 23, 22362 Lund

    Författare :Caroline Düringer; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; virology; mykologi; bakteriologi; virologi; mycology; bacteriology; Microbiology; chromatin; histones; apoptosis; alpha-lactalbumin; programmed cell death;

    Sammanfattning : HAMLET (human alpha-lactalbumin made lethal to tumour cells), a protein-lipid complex originally isolated from human milk, induces programmed cell death selectively in tumour cells. It consists of partially unfolded alpha-lactalbumin in complex with oleic acid. LÄS MER

  2. 2. Apoptosis induced by a human milk protein complex. Cellular and structural studies in tumour cells and bacteria

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Anders Håkansson; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; nuclear uptake; caspases; mitochondria; S. pneumoniae; alpha-lactalbumin; milk; breast-feeding; Apoptosis; tumour cells; transplantation; Immunologi; serologi;

    Sammanfattning : Human milk contains a vast array of bioactive molecules, with nutritional and protective functions. This thesis describes the effects of a human milk protein complex, MAL, on tumour cells and bacteria. During our studies on the anti-adhesive properties of human milk we observed that a milk fraction killed tumour cells. LÄS MER

  3. 3. Apoptosis and tumor cell death pathways in response to HAMLET

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Oskar Hallgren; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Klinisk biologi; apoptosis; autophagy; alpha-lactalbumin; Clinical biology; programmed cell death; HAMLET; cell cycle;

    Sammanfattning : HAMLET (Human alpha-lactalbumin made lethal to tumor cells) is a molecular complex of alpha-lactalbumin and oleic acid, that induces programmed cells death in tumor cells but leaves healthy differentiated cells unaffected. It has a broad anti-tumor activity as more than 40 cell lines from different origin are sensitive. LÄS MER

  4. 4. Temporary neonatal exposure to whole and hydrolysed cow's milk proteins. Studies of macromolecular absorption and immunological variables

    Detta är en avhandling från Department of Paediatrics, Lund University

    Författare :Pekka O Juvonen; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta-lactoglobulin; ovalbumin; cow s milk proteins; antibodies; IgG; IgE; secretory IgA; alpha-lactalbumin; breast-feeding; Pediatrics; Pediatri; early infant feeding; casein hydrolysate; Human milk; cow s milk;

    Sammanfattning : The aim of this work was to study prospectively the effects of different feeding regimens during the first three days of life. A group of 129 infants were randomly assigned at birth to one of three feeding regimens: human milk (HM), cow's milk formula (CMF), or a casein hydrolysate formula (CHF). LÄS MER

  5. 5. Structure-function analysis of HAMLET (human alpha-lactalbumin made lethal to tumor cells)

    Detta är en avhandling från Division of Microbiology, Immunology and Glycobiology - MIG

    Författare :Jenny Pettersson; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha-lactalbumin HAMLET oleic acid protein folding tumor cell death;

    Sammanfattning : The human genome sequence encodes fewer proteins than expected, suggesting that one protein can have several functions and adjust their structure to meet different structural demands. Changes in tertiary structure have mostly been associated with disease and the most striking example is the prion protein, which changes from a mixed alpha-helical and beta-sheet conformation to the beta-sheet rich, disease causing iso-form. LÄS MER