Sökning: "allogeneic DCs"
Visar resultat 6 - 10 av 17 avhandlingar innehållade orden allogeneic DCs.
6. The HER2/neu oncoprotein and dendritic cells in immunity against tumors
Sammanfattning : It is now well established that small peptide epitopes bound to the major histocompatibility complex (MHC), derived from processed proteins synthesized by the tumor cells, can be recognized as antigens by cytotoxic T lymphocytes (CTLs). A number of tumor antigens recognized by CTLs on human melanomas have been defined, but less is known about antigens from other tumor types. LÄS MER
7. Dendritic cells in cancer immunotherapy
Sammanfattning : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. LÄS MER
8. Bioactive leishmanicidal alkaloid molecules from Galipea longiflora Krause with immunomodulatory activity
Sammanfattning : According to WHO, leishmaniasis is endemic in 98 countries, and has been placed ninth in a global analysis of infectious diseases. Treatment of leishmaniasis is based on pentavalent antimonials but toxicity and developing resistance have been reported. LÄS MER
9. Immunobiology of graft versus host disease in chemotherapy based conditioning : new mouse model
Sammanfattning : Introduction: Graft versus host disease (GVHD) is a life threatening complication of allogeneic hematopoietic stem cell transplantation. The pathophysiology of GVHD is rather complex and several factors including; conditioning; MHC disparity and donor/host immune system influences both development and intensity of GVHD. LÄS MER
10. Characterization of antigen-presenting cell function in vitro and ex vivo
Sammanfattning : Long-term protective immunity depends on proper initiation of professional antigen-presenting cells (APCs). Autoimmune disorders and certain infections can cause disease through modulation of APCs and thereby affecting the outcome of these diseases. LÄS MER