Sökning: "alleles"
Visar resultat 11 - 15 av 437 avhandlingar innehållade ordet alleles.
11. Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
Sammanfattning : Rheumatoid arthritis (RA) is a complex disease with autoimmune features primarily causing destruction in the joints of the body. Knowledge regarding risk indicators and causes are increasing but so far only a few genetic and very few environmental risk factors have been consistently identified. LÄS MER
12. Defining human adaptive immune gene diversity
Sammanfattning : The lymphocytes (B and T cells) of the adaptive immune system undergo variable (V), diversity (D), and junctional (J) gene recombination, resulting in highly diverse antigen receptor repertoires capable of recognizing a wide variety of invading pathogens. The B cell receptor (BCR) contains two identical heavy and light chains. LÄS MER
13. The MHC genes: variation and impact on life-history traits in house sparrwos
Sammanfattning : In birds the major histocompatibility complex (MHC) organization differs both among and within orders. Galliformes often have simple arrangements with few transcribed MHC genes whilst many songbirds (Passeriformes) have a complex arrangement with many MHC genes and also presence of pseudo-genes. LÄS MER
14. Correlation Between Phenotype and Genotype in Some Clinically Important Blood group Systems
Sammanfattning : In the past decade, the molecular basis for most of the blood group systems has been investigated intensively. Many blood group genes have been cloned and the polymorphisms of clinically significant blood group systems have been elucidated. LÄS MER
15. Definition of immunoglobulin germline genes by next generation sequencing for studies of antigen-specific B cell responses
Sammanfattning : Immunoglobulins play a critical role in the adaptive immune system, existing as cell surface-expressed B cell receptors and secreted antibodies. Circulating antibodies are the main correlate of protective immunity for most vaccines. LÄS MER