Sökning: "aldehydes"

Visar resultat 16 - 20 av 150 avhandlingar innehållade ordet aldehydes.

  1. 16. Stereoselective Nucleophilic Additions to Aldehydes and Development of New Methodology in Organic Synthesis

    Författare :Tessie Borg; Olof Ramström; Siméon Arseniyadis; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis is divided into four separate parts with nucleophilic addition to aldehydes as the common feature in three of them.The first part deals with the investigation of the stereochemical induction and elucidation of the factors that dictate the p-facial selectivities in Mukaiyama aldol addition to a- and a,b-heteroatom substituted aldehydes. LÄS MER

  3. 17. Stereoselective Nucleophilic Additions to Aldehydes and Synthesis of α-Amino-β- Hydroxy-Esters

    Författare :Jakob Danielsson; Peter Somfai; Hans Adolfsson; Tobias Rein; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric induction; stereochemical models; Mukaiyama; polar Felkin-Anh; Cornforth-Evans; 1; 3-dipole; aziridine; cycloaddition; amino alcohol; carbonylation; Heck reaction; quaternary stereocenter;

    Sammanfattning : This thesis deals with the development of new reaction methodology as well as stereochemical investigations. The first part concerns the investigation of 1,2- and merged 1,2- and 1,3- asymmetric induction in Mukaiyama aldol additions to α-heteroatom and α,β- heteroatom substituted aldehydes respectively. LÄS MER

  4. 18. Analysis of DNA adducts of some low molecular weight aldehydes : methods development and application in human biomonitoring

    Författare :Jia-Long Fang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malondialdehyde (MA), acetaldehyde (Aa) and methylglyoxal (MG) are ubiquitously present in the environment and endogenously formed in animals and humans. They have been shown to be genotoxic and to readily react with DNA to form DNA adducts under physiological conditions. LÄS MER

  5. 19. Total synthesis of enantiomerically pure natural products via chiral unsaturated aldehydes formed by ring-contraction of sugar epoxides

    Författare :Nicola Rehnberg; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 20. New approaches for synthesis and analysis of adducts to N-terminal valine in hemoglobin from isocyanates, aldehydes, methyl vinyl ketone and diepoxybutane

    Författare :Ronnie Davies; Margareta Törnqvist; Leif Kronberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbamoylation; modified-Edman procedure; 5- hydroxymethyl furfural; MISPE; biomarkers; Environmental chemistry; Miljökemi; miljökemi; Environmental Chemistry;

    Sammanfattning : Human exposure to harmful compounds in the environment, from intake via food, occupational exposures or other sources, could have health implications. Exposure to reactive compounds/metabolites can be identified and quantified as hemoglobin (Hb) adducts by mass spectrometry. LÄS MER