Sökning: "alcohol markers"

Visar resultat 1 - 5 av 54 avhandlingar innehållade orden alcohol markers.

  1. 1. Studies on new pharmacological treatments for alcohol dependence - and the importance of objective markers of alcohol consumption

    Författare :Andrea deBejczy; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol dependence; mirtazapine; varenicline; org 25935; alcohol markers; phosphatidylethanol; randomized controlled clinical trials RCT ; treatment; glycine transporter inhibitor; nAChR;

    Sammanfattning : This thesis will guide you through three randomized controlled trials (RCT) on three pharmacotherapies for alcohol dependence; the antidepressant drug mirtazapine, the smoking cessation drug varenicline and the glycine-uptake inhibitor Org 25935. The mirtazapine study was an investigator initiated single-center harm-reduction study with alcohol consumption measured by self-report in a diary as main outcome. LÄS MER

  3. 2. Epidemiology of venous thromboembolism with focus on risk markers

    Författare :Magdalena Johansson; Lars Johansson; Marcus Lind; Jan-Håkan Jansson; Gerd Lärfars; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thromboembolism; venous thrombosis; deep vein thrombosis; pulmonary embolism; incidence; risk markers; diabetes; glucose; alcohol consumption; alcohol dependence; physical activity; medicin; Medicine;

    Sammanfattning : Background: Venous thromboembolism (VTE) is a vascular disease with an incidence of approximately 140 cases per 100,000 person-years in adults. The incidence of VTE has increased over the last decades, and more than 20% of affected individuals die in the first year after diagnosis. LÄS MER

  4. 3. Serotonergic aspects on high consumption of alcohol in humans. Experimental and clinical studies

    Författare :Matts Eriksson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol; alcohol-dependence; serotonin; SSRI; MAO-B; DRD2 A1 A2 alleles; fenfluramine; mood;

    Sammanfattning : In animal studies an association between alcohol intake and central serotonergic function has been demonstrated. There are also evidence for altered serotonergic neurotransmission in subgroups of alcohol-dependent subjects. LÄS MER

  5. 4. The influence of alcohol on bone metabolism and fracture healing

    Författare :Fredrik Nyquist; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; traumatology; orthopaedics; Surgery; fracture prediction.; fracture healing; bone mineral density; Alcohol; post-traumatic osteopenia; fracture; ortopedi; traumatologi; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Sammanfattning : The influence of alcohol on bone metabolism, fracture and fracture healing was evaluated in men and male rats by measurements of bone mineral density (BMD), biochemical markers and biomechanical testings. Retrospectively, 199 male patients hospitalized for tibia shaft fractures were studied. Forty-nine were judged as problem drinkers. LÄS MER

  7. 5. Chronic hepatitis C infection. With special reference to prevalence, aggravating factors and longterm outcome

    Författare :Hans Verbaan; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; alpha1-antichymotrrypsin; kollagen markers; hepatocellular cancer; cirrhosis; Hepatitis C infection; alcohol; Gastroenterologi;

    Sammanfattning : Since the discovery of hepatitis C virus (HCV) in 1989, it has proved to be a formidable health problem with a major impact on morbidity and mortality throughout the world. In this investigation, patients with chronic hepatitis C infection have been studied with special reference to prevalence, aggravating factors and longterm outcome. LÄS MER