Sökning: "albumin binding protein"
Visar resultat 1 - 5 av 70 avhandlingar innehållade orden albumin binding protein.
1. NMR Studies of Bacterial Albumin-Binding Modules
Sammanfattning : Peptostreptococcus magnus and group C/G streptococci are Gram-positive cocci that are part of the normal flora and reside in more or less the same locations in the host. Protein G of group C/G streptococci was originally described as binding IgGFc of several species and later shown to also bind human serum albumin and albumins from various animal species. LÄS MER
2. Protein engineering to explore and improve affinity ligands
Sammanfattning : In order to produce predictable and robust systems forprotein purification and detection, well characterized, small,folded domains descending from bacterial receptors have beenused. These bacterial receptors, staphylococcal protein A (SPA)and streptococcal protein G (SPG), possess high affinity to IgGand / or HSA. LÄS MER
3. An albumin-binding domain as a scaffold for bispecific affinity proteins
Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER
4. Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes
Sammanfattning : Several bacterial species express surface proteins with affinity for the Fc part of human IgG. This thesis describes evolutionary and functional studies of protein H, an IgGFc-binding surface protein of the human pathogen Streptococcus pyogenes. LÄS MER
5. Recombinant subunit vaccines : protein immunogens
Sammanfattning : Recombinant techniques provide valuable tools for thedevelopment of modern subunit vaccines. In this thesisdifferent systems for production of recombinant subunitvaccines are presented. The strategies investigated includeprotein immunogens, live bacterial vectors and nucleicacids. LÄS MER